Protein Alignment HPN and CG7542

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 70/265 - (26%)
• Similarity: 118/265 - (44%)
• Gaps: 40/265 - (15%)

Human   163 IVGGRDTSLGRWPWQVSLRY---DGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV-- 222
            |..|....:|::|:|..|..   :.:..|||:|:|..|::|||||......|    .|:.||:
  Fly    27 ITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWIITAAHCMDGAESV----TVYLGAINI 87

Human   223 ---AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQA 284
               ::.....:.:....::.|..|:      :....|||:|:.|.:.:..|:.|:...||..
  Fly    88 GDESEEGQERIMVEKSGIIVHSNYM------ASTVVNDISLIRLPAFVGFTDRIRAASLPRR--- 143

Human   285 LVDGKICT-------VTGWGNTQYYGQQAG-VLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 341
             ::|:..|       .:|||.......... ||:...:||:.:.:|.  .::...:..||.|..
  Fly   144 -LNGQFPTYESIRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLCR--MYWSGAVSEKMICMS- 204

Human   342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGVYTKVSDFREWIFQAI 404
            ...|...|.||||||.|.:...|.    .|.|..|:||  ||.:. .|.|:|::|.:.:||...|
  Fly   205 TTSGKSTCHGDSGGPLVYKQGNSS----YLIGSTSFGTSMGCQVG-FPAVFTRISSYLDWILNHI 264

Human   405 KTHSE 409
            ..|::
  Fly   265 IAHNK 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736
		Tryp_SPc	163..400	CDD:238113	66/254 (26%)
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	68/257 (26%)