Protein Alignment HPN and CG10663

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_001097592.1
• Gene: CG10663 / 39421
• FlyBaseID: FBgn0036287
• Length: 748
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 97/267 - (36%)
• Similarity: 133/267 - (49%)
• Gaps: 40/267 - (14%)

Human   154 GRRKLP-VDRIVGGRDTSLGRWPWQVSL--RYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRW 215
            |||.:. :.:|:|||....|.|||||::  |:..| .|||:|::..||||||||.   .:||
  Fly   497 GRRSMSNMLKIIGGRAARKGEWPWQVAILNRFKEA-FCGGTLIAPRWVLTAAHCV---RKVL--- 554

Human   216 RVFAGAVAQASPHGL--------QLGVQAVVYHGGYLPFRDPNSEENS--NDIALVHLSSPLPLT 270
                  ..:...|.|        ||.|.....|        ||.::.:  :|:||:.|...:..|
  Fly   555 ------FVRIGEHNLNYEDGTEIQLRVMKSYTH--------PNFDKRTVDSDVALLRLPKAVNAT 605

Human   271 EYIQPVCLPAAGQALVDGKICTVTGWG---NTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQI 332
            .:|...|||...|||.....||:.|||   |....|  ..||.:|.||||....|... :|...|
  Fly   606 TWIGYSCLPQPFQALPKNVDCTIIGWGKRRNRDATG--TSVLHKATVPIIPMQNCRKV-YYDYTI 667

Human   333 KPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFR 397
            ...|||||:.:|.||.|.||||||.:|.|:......|.:.||.|:|.|||...|.|:|.||.::.
  Fly   668 TKNMFCAGHQKGHIDTCAGDSGGPLLCRDTTKPNHPWTIFGITSFGDGCAQRNKFGIYAKVPNYV 732

Human   398 EWIFQAI 404
            :|::..:
  Fly   733 DWVWSVV 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	3/4 (75%)
		Tryp_SPc	163..400	CDD:238113	93/251 (37%)
CG10663	NP_001097592.1	Tryp_SPc	506..735	CDD:214473	93/252 (37%)