Protein Alignment HPN and CG16998

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_648134.1
• Gene: CG16998 / 38847
• FlyBaseID: FBgn0035795
• Length: 258
• Species: Drosophila melanogaster
• Alignment Length: 262
• Identity: 80/262 - (30%)
• Similarity: 118/262 - (45%)
• Gaps: 35/262 - (13%)

Human   153 CGRRK---LPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHC--FPERNRVL 212
            ||.:.   .|.:|||||.:..:...||..|:...|.:.|..:|::..|::||.||  :|:
  Fly    12 CGHKTSALSPQERIVGGVEVPIHLTPWLASITVHGNYSCSSALITSLWLVTAGHCVQYPD----- 71

Human   213 SRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
             .:.|.||:.. ....|.:..|.:|:.|      .|.|.....|||||:.|.....|...||.|.
  Fly    72 -SYSVRAGSTF-TDGGGQRRNVVSVILH------PDFNLRTLENDIALLKLDKSFTLGGNIQVVK 128

Human   278 LPAAGQALVDGKICTVTGWGNTQYYGQQAGV-LQEARVPIISNDVCNGADFYGNQIKP---KMFC 338
            ||.....::. :...|.||||......::.. |:...|.:|:..:|.  ..|.:..:|   .|.|
  Fly   129 LPLPSLNILP-RTLLVAGWGNPDATDSESEPRLRGTVVKVINQRLCQ--RLYSHLHRPITDDMVC 190

Human   339 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQA 403
            |.  ..|.|.|.||||.|.|        .|....||||:..|||....|||||:::::..|||..
  Fly   191 AA--GAGRDHCYGDSGAPLV--------HRGSSYGIVSFAHGCADPHFPGVYTRLANYVTWIFNV 245

Human   404 IK 405
            ::
  Fly   246 LE 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	2/8 (25%)
		Tryp_SPc	163..400	CDD:238113	73/242 (30%)
CG16998	NP_648134.1	Tryp_SPc	24..242	CDD:214473	74/243 (30%)