Protein Alignment HPN and CG32270

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_728837.1
• Gene: CG32270 / 3772375
• FlyBaseID: FBgn0052270
• Length: 259
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 86/258 - (33%)
• Similarity: 117/258 - (45%)
• Gaps: 29/258 - (11%)

Human   148 AICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 212
            ::.::...|:.|  |||||..:.:...|..|::|..|...|||||::...|||||||..:.|.
  Fly    18 SVAEELELRRSP--RIVGGHPSDVWHQPHMVNIRRRGNFECGGSLVTPRCVLTAAHCLNDGNP-- 78

Human   213 SRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVC 277
            |.: |..|.|...|.......|:.::....|      :.....:|:||:.|..||. ....:|:.
  Fly    79 SDF-VVRGGVTYLSDMRNSRYVRKILMPSAY------SRTTLDHDVALLQLKQPLQ-ASIAKPIS 135

Human   278 LPAAGQALVDGKICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYG--NQIKPKMFCA 339
            |  |.::...|....|:|||.|...... ...||...|.::....|.  |.|.  ..|...||||
  Fly   136 L--AVRSPRPGSFVRVSGWGLTDSSSTSLPNQLQSVHVQVMPQRECR--DLYRGYRNITSSMFCA 196

Human   340 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG--CALAQKPGVYTKVSDFREWI 400
            ..| |..|||.||||||.|..:.|       |.|:||||..  ||....||||:.||...:||
  Fly   197 SVP-GLKDACAGDSGGPVVNSNGI-------LVGVVSWGRAHRCAARDSPGVYSDVSYLSDWI 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	1/10 (10%)
		Tryp_SPc	163..400	CDD:238113	81/241 (34%)
CG32270	NP_728837.1	Tryp_SPc	30..251	CDD:214473	82/242 (34%)