Protein Alignment HPN and CG30414

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_611789.2
• Gene: CG30414 / 37705
• FlyBaseID: FBgn0050414
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 92/319 - (28%)
• Similarity: 130/319 - (40%)
• Gaps: 72/319 - (22%)

Human   144 RFLAA-----IC--------------QDCGRRK---LPVDRIVGGRDTSLGRWPWQVSLRYDGAH 186
            :|:||     :|              ..||..|   :|:  |.||.|..|...||.|.:.  |..
  Fly     2 KFIAAGLALLVCSIQLGEGAPGHLLDSSCGTTKPEFIPM--ITGGADAGLFSNPWMVKVL--GEK 62

Human   187 LCGGSLLSGDWVLTAAHC----------------FP--------ERNRVLSRWRV------FAGA 221
            ||||||::..:|||||||                ||        .::..|.|.|:      |.|.
  Fly    63 LCGGSLITSRFVLTAAHCIVSTHMRVRLGEYKTRFPGKDCSRCVPKSYKLRRIRLGEYDTRFPGK 127

Human   222 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALV 286
            .. ..|...:|.|...:.|..|       :....|||.|:.:.|.:..::|::|:||...|. :.
  Fly   128 DC-CVPKSYELAVDRKILHADY-------NLNLDNDIGLLRMKSFVQYSDYVRPICLLVEGH-MA 183

Human   287 DGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQG 351
            :..|..:||||.|. .|..:..||.|.|.......|...  :..|:.....||.....  |||.|
  Fly   184 ESPIFNITGWGVTN-DGTPSRRLQRATVYNTDLHFCRSK--FTKQVDESQICAAGTNS--DACHG 243

Human   352 DSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEA 410
            |||||...:...:.:......|:||:|:  |......|||.|:..|:||..||:..|.|
  Fly   244 DSGGPLSAQVPFAGSWLTFQYGLVSYGS--AACHSFSVYTNVTHHRDWIVNAIEDFSRA 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	7/36 (19%)
		Tryp_SPc	163..400	CDD:238113	78/266 (29%)
CG30414	NP_611789.2	Tryp_SPc	41..290	CDD:238113	78/266 (29%)