Protein Alignment HPN and zetaTry

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_523691.1
• Gene: zetaTry / 36216
• FlyBaseID: FBgn0011556
• Length: 280
• Species: Drosophila melanogaster
• Alignment Length: 268
• Identity: 99/268 - (36%)
• Similarity: 139/268 - (51%)
• Gaps: 35/268 - (13%)

Human   149 ICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDG--------AHLCGGSLLSGDWVLTAAHCF 205
            :.:|...:.:|..|||||..|.:.:.|:|:||||.|        .|.||||:.:...::|||||.
  Fly    25 LLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV 89

Human   206 PERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT 270
              ...|.|:::|.||...|....|:...|:.:|.|.||.     :....:||||::.:..||||.
  Fly    90 --IGTVASQYKVVAGTNFQTGSDGVITNVKEIVMHEGYY-----SGAAYNNDIAILFVDPPLPLN 147

Human   271 EY-IQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCN------GADFY 328
            .: |:.:.|  |.:..::|.:..|:|||.|...|..:..|....|||:||::|:      |.:.|
  Fly   148 NFTIKAIKL--ALEQPIEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETY 210

Human   329 GNQIKPKMFCAG-YPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTK 392
              :|...|.||| ...||.||||||||||....|        .|.|:||||..|||...||||..
  Fly   211 --RITSAMLCAGKRGVGGADACQGDSGGPLAVRD--------ELYGVVSWGNSCALPNYPGVYAN 265

Human   393 VSDFREWI 400
            |:..|.||
  Fly   266 VAYLRPWI 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	1/9 (11%)
		Tryp_SPc	163..400	CDD:238113	94/252 (37%)
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	95/253 (38%)