Protein Alignment HPN and CG17571

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_610109.1
• Gene: CG17571 / 35409
• FlyBaseID: FBgn0259998
• Length: 258
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 102/276 - (36%)
• Similarity: 143/276 - (51%)
• Gaps: 35/276 - (12%)

Human   131 LLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLR-YDGAHLCGGSLLS 194
            ||.|:::.      .|||.|........|..|||.|.|..:..:|:|||:: ..|:|.|||||:.
  Fly     5 LLSVVALV------ALAASCHGNPGLDFPFGRIVNGEDVDIENYPYQVSVQTTKGSHFCGGSLID 63

Human   195 GDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIA 259
            .:.|||||||.  ::...|..:|..|:.:::| .|..:.|:|..||.||      ||:...||:|
  Fly    64 SETVLTAAHCM--QSYAASELQVRVGSTSRSS-GGEVVTVRAFKYHEGY------NSKLMINDVA 119

Human   260 LVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQY-YGQQAGVLQEARVPIISNDVCN 323
            ::.||||:..|..|:.:.|  |....|.|....|:|||.|.: :......||:..|.::....|
  Fly   120 IIKLSSPVRQTSKIRAIEL--ADSEAVSGTNAVVSGWGTTCFLFCSSPDTLQKVEVDLLHYKDC- 181

Human   324 GADFY---GNQIKPKMFCA-GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALA 384
            .||.|   .:.|...|.|| |..:   ||||||||||.|.::        :|.|:||||:|||..
  Fly   182 AADTYNYGSDSILETMVCATGEKK---DACQGDSGGPLVADN--------KLVGVVSWGSGCAWT 235

Human   385 QKPGVYTKVSDFREWI 400
            ..||||..|:..|.||
  Fly   236 GYPGVYADVASLRSWI 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	7/27 (26%)
		Tryp_SPc	163..400	CDD:238113	91/242 (38%)
CG17571	NP_610109.1	Tryp_SPc	30..251	CDD:214473	92/243 (38%)