Protein Alignment HPN and CG9672

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_573151.1
• Gene: CG9672 / 32651
• FlyBaseID: FBgn0030777
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 63/260 - (24%)
• Similarity: 102/260 - (39%)
• Gaps: 41/260 - (15%)

Human   159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVA 223
            |..||.||.|..||:.|:|.:|...|::.||..::...:.|||..|.....:. :.|.....||.
  Fly    21 PQGRIAGGEDAVLGQLPYQAALSIGGSYNCGAVIIGQRYALTALSCVCSDGKD-TPWAAVLFAVT 84

Human   224 QASP---HGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQAL 285
            ..|.   :|.|:.|:.:..        :||.......|||:.|...:..:|.:.  .:|.:....
  Fly    85 VGSVDLYNGKQIRVEEITI--------NPNYSTLKTGIALLRLQEEITFSETVN--AIPLSQDVP 139

Human   286 VDGKICTVTGWGNT------QYYGQQAG---VLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 341
            ..|....|:|||.|      .:...|.|   |:......:.:.|....||       .::.|.|:
  Fly   140 PMGSQVEVSGWGRTTESEVNMHRTLQIGAAEVMAPRECALANRDELLVAD-------DQVLCLGH 197

Human   342 -PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405
             ...||  |.||.|||.|.:.        :|.|:.:...|......|..:..::...:||.|.::
  Fly   198 GRRQGI--CSGDIGGPAVYQG--------QLVGLGAQILGECGGMLPERFISIAANYDWIQQQLQ 252

Human   406  405
              Fly   253  252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	63/260 (24%)
		Tryp_SPc	163..400	CDD:238113	58/249 (23%)
CG9672	NP_573151.1	Tryp_SPc	24..247	CDD:214473	59/250 (24%)