Protein Alignment HPN and CG31681

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_722789.1
• Gene: CG31681 / 318882
• FlyBaseID: FBgn0051681
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 87/251 - (34%)
• Similarity: 122/251 - (48%)
• Gaps: 25/251 - (9%)

Human   159 PVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVA 223
            |.:|||||....:...|||||::.:..|.|||.:.|...:||||||.  .|..::...|.||: :
  Fly    25 PEERIVGGSYIPIEYVPWQVSVQNNSLHCCGGVIYSDRAILTAAHCL--SNVTVTDLSVRAGS-S 86

Human   224 QASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDG 288
            ..|..|..|.|...:.|..|:|     ...|..|||::.|.:||.|...::.:  |.|.|..|.|
  Fly    87 YWSKGGQVLKVLKTIAHPKYVP-----KLYNPYDIAVLILEAPLRLGGTVKKI--PLAEQTPVAG 144

Human   289 KICTVTGWGNTQYYGQQAG----VLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDAC 349
            .|...:|||.|:   :.:.    :||...|.|::...|..|..:.| |...|.||.....  |.|
  Fly   145 TIVLTSGWGYTR---ENSSFLWPILQGVHVAILNRTDCLKAYKHVN-ITIDMICADGQRW--DTC 203

Human   350 QGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIK 405
            |||||||.:   ..::....:|.|:||||.||  ...||||..::.|..||...:|
  Fly   204 QGDSGGPLI---ETTKGGHRQLIGMVSWGDGC--GTNPGVYEDIAFFHNWIKYTVK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	87/251 (35%)
		Tryp_SPc	163..400	CDD:238113	82/240 (34%)
CG31681	NP_722789.1	Tryp_SPc	28..249	CDD:214473	83/241 (34%)