Protein Alignment HPN and CG30083

DIOPT Version :10

• Sequence 1: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_725492.3
• Gene: CG30083 / 246444
• FlyBaseID: FBgn0050083
• Length: 279
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 74/277 - (26%)
• Similarity: 129/277 - (46%)
• Gaps: 51/277 - (18%)

Human   152 DCGRRKLPVDRIVGGRDTSLGRWPWQVSL-RYDGAH----LCGGSLLSGDWVLTAAHCFPERNRV 211
            :||...:. .:|:.|::...|..||...: :|:...    :|||:|:...:||:||||. :|:::
  Fly    24 NCGYPDIS-PKIMHGQNAENGTNPWMAYIFKYNDKEVAELVCGGTLIHKQFVLSAAHCI-KRDQI 86

Human   212 L-------SRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDP--NSEENSNDIALVHLSSPL 267
            |       |..|.|  ||.:|                    ||:.  .:...||||.::.:...:
  Fly    87 LAVRLGEHSSSRYF--AVTKA--------------------FRNKYFTTGSYSNDIGILRIQPIV 129

Human   268 PLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGN-- 330
            .....|:|:|:......:.:.|.....|||.|: ....:.||:...:    |:: |.::.|..
  Fly   130 KFNAVIRPICIITDPTKVPNVKTFKAAGWGKTE-NETFSKVLKTVEL----NEL-NASECYNMLW 188

Human   331 -QIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVS 394
             .:.....|||:|:|  |.|.||||||.:....:..:.|:...||:|:|:  :|...|||||::|
  Fly   189 VNVTESQICAGHPDG--DTCAGDSGGPLIHPVYMDGSLRYVQLGIISFGS--SLCNSPGVYTRLS 249

Human   395 DFREWIFQAIKTHSEAS 411
            .|.:||...:..::..|
  Fly   250 SFIDWILMVVDNYTVRS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	2/6 (33%)
		Tryp_SPc	163..400	CDD:238113	69/253 (27%)
CG30083	NP_725492.3	Tryp_SPc	34..255	CDD:238113	69/253 (27%)