DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15643 and Spring1

DIOPT Version :9

Sequence 1:	NP_001285276.1	Gene:	CG15643 / 32489	FlyBaseID:	FBgn0030654	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001074705.1	Gene:	Spring1 / 76792	MGIID:	1924042	Length:	205	Species:	Mus musculus

Alignment Length:	212	Identity:	95/212 - (44%)
Similarity:	126/212 - (59%)	Gaps:	16/212 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AAL--TRLLRRRIVYIVLVVLLLIYGFGHIFDRDSFSGLHYDEYVVQ-RTRPLLWTQQLLAPEEQ 65
            |||  .||||:|.|..::..|.|:|.....|.::..:....:...|| |.:|:.|..|.    ..
Mouse     5 AALLWRRLLRKRWVLALVFGLSLVYFLSSTFKQEERAVRDRNLLQVQDREQPIPWKVQF----NL 65

  Fly    66 LNRTRGDPEARCRNSVQGRQWLADERGFVCRREEVLTNGCCNLELPGIGYYSCRTCNTSTHCCGV 130
            .|.:|  |..:|||||||:..|.||.|:||.|:::|.||||::.:|....|.|..| .:..||..
Mouse    66 GNSSR--PSNQCRNSVQGKHLLTDELGYVCERKDLLANGCCDVSVPSTKQYCCDGC-LANGCCEA 127

  Fly   131 YEYCVSCCLHPGQQPLLERVL-QAPNTPKYIFASVTDHFELCLVKCRTNSHSVEHENKYRDPAAK 194
            |||||||||.|.:|.||||.| :|....:.:|.:|.|||||||.||||:|.||:|||.||||.||
Mouse   128 YEYCVSCCLQPSKQLLLERFLNRAAVAFQNLFMAVEDHFELCLAKCRTSSQSVQHENTYRDPIAK 192

  Fly   195 HCYGLTDAHESQRDVAP 211
            :|||     ||..::.|
Mouse   193 YCYG-----ESPPELFP 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15643	NP_001285276.1	DUF2054	74..197	CDD:287222	67/123 (54%)
Spring1	NP_001074705.1	DUF2054	74..195	CDD:370892	67/121 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849508
Domainoid	1	1.000	151	1.000	Domainoid score	I4368
eggNOG	1	0.900	-	-		E1_KOG3136
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32599
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4188
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007174
OrthoInspector	1	1.000	-	-		oto93678
orthoMCL	1	0.900	-	-		OOG6_106237
Panther	1	1.100	-	-	LDO	PTHR13481
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5724
SonicParanoid	1	1.000	-	-		X5284
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.780