DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7860 and asrgl1

DIOPT Version :9

Sequence 1:	NP_001285275.1	Gene:	CG7860 / 32488	FlyBaseID:	FBgn0030653	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001013547.1	Gene:	asrgl1 / 541402	ZFINID:	ZDB-GENE-050320-102	Length:	310	Species:	Danio rerio

Alignment Length:	326	Identity:	125/326 - (38%)
Similarity:	183/326 - (56%)	Gaps:	25/326 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PVLLIHGGAGDISDSRIAGKFAGIKQALRSAWGLLSPDNGSGGGSALDAVEAAVRSMELDENFNA 68
            ||:::|||||.|...|......|:|:|.|:.:.:|     ..||||:|||..||..||.:..|||
Zfish     3 PVVVVHGGAGHIPKERTEESTIGVKEAARTGYAIL-----QRGGSAVDAVVEAVALMETNPRFNA 62

  Fly    69 GYGSCLNTSGQVELEASLMEGRDLRAGCITLLRDVMHPITVARRLMEKQRHTFLGGAAAQELALA 133
            |.||.||..|:||::|.:|:||.|.:|.::.:|.:.:|:.:||.:|||.:|..|....|.:.|.:
Zfish    63 GRGSVLNIKGEVEMDALVMDGRTLDSGAVSAVRRIANPVQLARLVMEKTKHLCLTAEGASKFARS 127

  Fly   134 TGSERLQPGALVTEGARLTLKEFEDQVAQGKDPFFARTELTDDKPVPKTDPSGETVGAVAMDASG 198
            .|...:...:|:|:.|::..|       :..:|        |..||........||||||:|..|
Zfish   128 MGVPEVPEESLITDYAKMRWK-------KNLEP--------DANPVECQMGKMGTVGAVAVDMDG 177

  Fly   199 QIVVGTSTGGITGKWPGRIGDTPILGSGTYADNCRGGVSTTGHGETLMRYNLAQRILSAMEYQGL 263
            .|...|||||:..|..||:||||.:|.|.||||..|.||.|||||.:|:..|::.:|..|| ||.
Zfish   178 NIACATSTGGMINKMEGRVGDTPCVGCGGYADNKIGAVSPTGHGEAIMKVTLSRLVLFHME-QGK 241

  Fly   264 SAQAAADKECREMTKRLGGTGGAIVVGHSGDLGISFTSRRMAWGYVQDGTIFYGIEGQVVHQEPF 328
            :.:.|:|.....|.:|:.|.||.:||.|:|.....|:|.:|:|...|.|.:.:|:    .|.:.|
Zfish   242 TPEEASDLALAYMKERVDGLGGVVVVDHNGTWAARFSSLQMSWAAAQQGKLHFGL----FHGDHF 302

  Fly   329 T 329
            |
Zfish   303 T 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7860	NP_001285275.1	PRK10226	1..311	CDD:182319	119/306 (39%)
CG7860	NP_001285275.1	ASRGL1_like	3..312	CDD:271338	120/307 (39%)
asrgl1	NP_001013547.1	ASRGL1_like	3..290	CDD:271338	120/307 (39%)
		Substrate binding. /evidence=ECO:0000250	195..198		1/2 (50%)
		Substrate binding. /evidence=ECO:0000250	218..221		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574711
Domainoid	1	1.000	214	1.000	Domainoid score	I2687
eggNOG	1	0.900	-	-		E1_COG1446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3536
OMA	1	1.010	-	-		QHG60905
OrthoDB	1	1.010	-	-		D520430at33208
OrthoFinder	1	1.000	-	-		FOG0000907
OrthoInspector	1	1.000	-	-		otm25106
orthoMCL	1	0.900	-	-		OOG6_102189
Panther	1	1.100	-	-	O	PTHR10188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1943
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770