Protein Alignment CG42299 and NSMCE2

DIOPT Version :10

• Sequence 1: NP_727866.2
• Gene: CG42299 / 32487
• FlyBaseID: FBgn0259195
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: XP_016868819.1
• Gene: NSMCE2 / 286053
• HGNCID: 26513
• Length: 249
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 45/198 - (22%)
• Similarity: 76/198 - (38%)
• Gaps: 50/198 - (25%)

  Fly    17 AEVVSNSSDDGEKL-----------LTKNSSNTIEKSEEVCKERPEAVEQMRIDVNNSL------ 64
            |||.|..|.|...:           ..|...:||...:|   ||||.:..:::.|....
Human    55 AEVSSEYSMDKAMVEFATLDRQLNHYVKAVQSTINHVKE---ERPEKIPDLKLLVEKKFLALQSK 116

  Fly    65 -EDTNYMN--------------------AVESEAQKNIAGLDEDLIMEDFGVEVVPFHDPWSKLL 108
             .|.::.|                    ..:.||. ...|:|||:|:..   ....|..|.:|..
Human   117 NSDADFQNNEKFVQFKQQLKELKKQCGLQADREAD-GTEGVDEDIIVTQ---SQTNFTCPITKEE 177

  Fly   109 IKHPVRNKRCGHIYDRETVLMII----KDNIGILCPVRDCPNLSDIKLEHLVKDPDVEQELQKRK 169
            :|.||:||.|||.|:.:.::.:|    |......||...|.: :||:...|::|..:.:.::...
Human   178 MKKPVKNKVCGHTYEEDAIVRMIESRQKRKKKAYCPQIGCSH-TDIRKSDLIQDEALRRAIENHN 241

  Fly   170 SDK 172
            ..:
Human   242 KKR 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42299	NP_727866.2	SPL-RING_NSE2	103..167	CDD:438313	20/67 (30%)
NSMCE2	XP_016868819.1	SPL-RING_NSE2	169..239	CDD:438313	21/70 (30%)