Protein Alignment Ac13E and Gyc88E

DIOPT Version :10

• Sequence 1: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Alignment Length: 847
• Identity: 195/847 - (23%)
• Similarity: 310/847 - (36%)
• Gaps: 210/847 - (24%)

  Fly   251 GDPSNRILILRIMAHLSVHLVGVHVLIMNLVRMRGTFMKVGQNLLVRRQLEMEKQLKEKM----- 310
            |.|....|...|...|.::.:.:|....:|: :.||...|...|.:.::.:..|:|:|.|
  Fly   320 GTPVMPDLTSLITTGLYINDLSMHDFSRDLM-LAGTQQSVELKLALDQEQQKSKKLEESMRLLDE 383

  Fly   311 --------IHSVMPPKVADMLLNEGGPSGLDAGGLPPESHYMRPRASNDVKSLFRPFHMHSMENV 367
                    ::.::|.:|||.|.....|.                    |...:|        ::|
  Fly   384 EMRRTDELLYQMIPKQVADRLRRGENPI--------------------DTCEMF--------DSV 420

  Fly   368 SILFADIVGFTRMSSTKTAEQLVEILNDLFERFDDLCSLSGCEKISTLGDCYYCVSGCPEPRADH 432
            ||||:|||.||.:.|..|..::|.:||.::..||.|...:...|:.|:||.|..|:|.|:..|:|
  Fly   421 SILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANH 485

  Fly   433 AICCVEMGLGMIDAMRCF-DAQRHEGVKMRVGVHTGTVLCGIVGTRRVKFDVWSNDVSLANKMES 496
            |....:|.|.|:||:... |....:.:::|||||:|.|:.||||.:..::.::.:.|:.|::|||
  Fly   486 AERVCDMALDMVDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMES 550

  Fly   497 SGKPEQVHISQETSSFLGDAY-YLEEGE-EVFGH---RTYFVVGRRRDFTRTNSLSPSMPANATG 556
            :....:||||:.|...:|..| .:|.|| :|.|.   .||::..|..          .:|...|
  Fly   551 TSIAMKVHISESTKVLIGPNYKIIERGEIDVKGKGTMGTYWLEEREN----------RLPLQLT- 604

  Fly   557 SSLLLPGAHGASLSQSATNVSAVQPNVPPASPVGQLSSSLNP--SPVLSMRPRLTSLSMKMRKKS 619
                           :|..|..:.| ||| :|..:..:.:.|  .|:..|.|...||:..|
  Fly   605 ---------------AALQVHPLSP-VPP-TPTPKTKAIMPPVSKPLTPMMPVSVSLAASM---- 648

  Fly   620 QSRDRDVERGIIHPAAAGIPPVIVVRERPKI--IITTKSLPGSLDSDEQPPVSPPL--------L 674
                          ..:.:|.|.|:.....|  :..|.:....:....|..|:..|        |
  Fly   649 --------------PTSNVPAVDVMASSSSISGLALTAAAAAHMSLHHQAVVAEALTGASVEVAL 699

  Fly   675 PP-----------ANPPAAETRSKIKLKVWKIPRFLKRFEDLTNRSSCGGS-SSAGHLDKERERE 727
            |.           ...|:.:..|:|...|        .|:|:..||..... .|....|:||.||
  Fly   700 PSVASGATGAAAGGGAPSDDRNSRIYSPV--------TFKDVARRSVANSPVRSCAQPDQERRRE 756

  Fly   728 RE---------KEKEELHQHNQLNPEETL-------AFMDNQMQNGNGCGYQQLPVLVESNHRTQ 776
            ..         :...|:.....|:.||.|       :.:.|...|.:.||:...|..     |..
  Fly   757 SRSNSTGHVFMRTPSEIFGSLILDTEEFLEDLQISRSSLANNNNNQSPCGFSPTPPF-----RIG 816

  Fly   777 TLDIPAARPVLHHAATSTALAS-SVLRSPEAGVSGGGGCCSPGQYSMYDDIIDVRSYISQSRSDI 840
            :.. |..||......|...||: ..|..|....:.....||..  |:..|.......|:.|.|
  Fly   817 SAP-PKPRPSNPDKFTPEELAAMDQLTPPSTAPARETASCSSA--SLDRDKATKLKKITFSNS-- 876

  Fly   841 SPFGRSGSYRSQCGRQSTGGVNGAGPAGVGAEGRAGTSQTAPPVEQSP-LPRPRASTLATGRPTP 904
                           .|.........|.|....|.    .:||:..:| :...:|||.......|
  Fly   877 ---------------SSLDATTPTALAAVVCPMRT----KSPPMAVAPVMHMVQASTSKGDGQRP 922

  Fly   905 NSLEPGPSSTSPCCLPAPGNSVGGGGIFPPTHSRQSSICPSATSRKDSGIKSNSRRSSIQQQIYA 969
            .|.:    |.|...|.:|          ||..|.      ||.:|..|..|:..:.....:|..|
  Fly   923 GSKD----SVSSISLHSP----------PPHRSN------SAPARPHSMSKAARKAFLAAKQTKA 967

  Fly   970 LNQTAISQHRVSGYFTSSTSSISNL----------GEVQGLGLPLAVQPPP-------PLLMPAC 1017
            :.:.......|....:.|.:..:|:          |::...|.||.:.|||       ..|||:.
  Fly   968 MEKLDKMIEEVQEVESQSVAKAANMRLALYGHDGGGDLAAGGCPLFLPPPPQQQQQQQQSLMPSS 1032

  Fly  1018 SS 1019
            .|
  Fly  1033 IS 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	70/230 (30%)
		PHA03307	836..>1015	CDD:223039	39/196 (20%)
		Guanylate_cyc	1388..1575	CDD:425528
Gyc88E	NP_001036711.1	HNOB	2..163	CDD:462233
		HNOBA	201..404	CDD:462234	19/84 (23%)
		CYCc	383..571	CDD:214485	65/215 (30%)
		PHA03307	794..>955	CDD:223039	45/209 (22%)