Protein Alignment Ac13E and CG10738

DIOPT Version :9

• Sequence 1: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_729905.2
• Gene: CG10738 / 39516
• FlyBaseID: FBgn0036368
• Length: 1250
• Species: Drosophila melanogaster
• Alignment Length: 604
• Identity: 156/604 - (25%)
• Similarity: 231/604 - (38%)
• Gaps: 163/604 - (26%)

  Fly     5 RRQSVS-SRAMPPGV-LVNDSRANS--------TDDIQIALAPHIQTYLSQTGRRHSCCSVMLPV 59
            |::||. :|.|...: |:.|:|.::        ||...|.:   |..|         |....|..
  Fly   608 RKKSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICI---ISEY---------CTRGSLKD 660

  Fly    60 AFERAAAKSWLDPKFDSPVLEEQYQASVFPH---VRMRYRFTLSYILLCSLMWCL------YFVV 115
            ..|....|  ||..|.:.::.:..:..::.|   :|.......|..|:.| .|.:      .|..
  Fly   661 ILENEDVK--LDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDS-RWVVKLTDFGLFAF 722

  Fly   116 DGGSEDFWRPISSSFSMLSLVTIMALCFTHWDLYREHRTVTSAVTALLLCG-ASLAFLTYTGRAF 179
            ..|.||         |...:..:.|.|...  |||        ...||..| :||...|..|.|:
  Fly   723 KQGIED---------SSTDMQHMSAKCLKL--LYR--------APELLRQGPSSLVMGTQRGDAY 768

  Fly   180 S-------------PLGHFAI----CLEIVLL------IYTALPMPLWLGASTAISYSIAFEMVS 221
            |             |.|...:    ||:.||.      .|.....||          ..||:.||
  Fly   769 SFGILLYEMHVRRGPFGETGLTPMQCLQKVLQPQDYLNPYRPSLQPL----------ETAFDCVS 823

  Fly   222 HMVIGCSAIHGGPMHGGGGAAGGSGMEANGDPSNRILILRIMAHLSVHLVGVHVLIMNLVRMRGT 286
            ..:..|.|..                     |.:|.....|...|.....|:...|.:  .|...
  Fly   824 ECLRECWAER---------------------PEDRPDFKTIRTKLRPLRKGMRPNIFD--NMMAM 865

  Fly   287 FMKVGQNL--LV---RRQLEMEKQLKEKMIHSVMPPKVADMLLNEGGPSGLDAGGLPPESHYMRP 346
            ..|...||  ||   ..||:.||:..:.::|.::|..|||. |.:|..       :.|| ||
  Fly   866 MEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQ-LKKGHK-------VDPE-HY--- 918

  Fly   347 RASNDVKSLFRPFHMHSMENVSILFADIVGFTRMSSTKTAEQLVEILNDLFERFDDLCSLSGCEK 411
                              |.|||.|:||||||.||:..|..|:|:.||||:..||.:.......|
  Fly   919 ------------------EQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYK 965

  Fly   412 ISTLGDCYYCVSGCPEPRAD-HAICCVEMGLGMIDAMRCFDAQRHEGVK---MRVGVHTGTVLCG 472
            :.|:||.|..|||.|....| ||.....|.|.::.|:..|.. ||....   :|:|:|:|.|..|
  Fly   966 VETIGDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKI-RHRPTNRLLLRIGIHSGPVCAG 1029

  Fly   473 IVGTRRVKFDVWSNDVSLANKMESSGKPEQVHISQETSSF---LGDAYYLEEG----EEVFGHRT 530
            :||.:..::.::.:.|:.|::|||||.|.::|.|.:....   ||..::.|.|    :.....||
  Fly  1030 VVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLGGYHFAERGVISMKGKGDQRT 1094

  Fly   531 YFVVGR------RRDFTRT 543
            |:::|.      ||.:.|:
  Fly  1095 YWLLGEDEEARTRRTYERS 1113

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	73/222 (33%)
		Guanylate_cyc	361..535	CDD:278633	65/184 (35%)
		CYCc	1362..1556	CDD:214485
		Guanylate_cyc	1388..1575	CDD:278633
CG10738	NP_729905.2	PBP1_Speract_GC_like	41..441	CDD:107365
		ANF_receptor	67..416	CDD:279440
		PK_GC-A_B	570..853	CDD:270944	64/309 (21%)
		TyrKc	597..847	CDD:197581	63/303 (21%)
		HNOBA	<862..907	CDD:285003	15/45 (33%)
		CYCc	886..1078	CDD:214485	73/222 (33%)
		Guanylate_cyc	913..1099	CDD:278633	69/208 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900