Protein Alignment Ac13E and Gucy1b2

DIOPT Version :9

• Sequence 1: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: XP_011243363.2
• Gene: Gucy1b2 / 239134
• MGIID: 2660873
• Length: 829
• Species: Mus musculus
• Alignment Length: 325
• Identity: 89/325 - (27%)
• Similarity: 152/325 - (46%)
• Gaps: 53/325 - (16%)

  Fly   295 LVRRQLEMEKQLKEKMIHSVMPPKVADMLLNEGGPSGLDAGGLPPESHYMRPRASNDVKSLFRPF 359
            ::...|.:||:..|.::::::|..||:. |.||  ..:.||
Mouse   538 VLSNHLAIEKKKTETLLYAMLPEHVANQ-LKEG--KKVAAG------------------------ 575

  Fly   360 HMHSMENVSILFADIVGFTRMSSTKTAEQLVEILNDLFERFDDLCSLSGCEKISTLGDCYYCVSG 424
               ..|..:|||:|:|.||.:.:.....|:|.:||.::.:||.|.::....|:.|:||.|..|.|
Mouse   576 ---EFETCTILFSDVVTFTNICAACEPIQIVNMLNSMYSKFDRLTNIHDVYKVETIGDAYMVVGG 637

  Fly   425 CPEPRADHAICCVEMGLGM-IDAMRCFDAQRHEGVKMRVGVHTGTVLCGIVGTRRVKFDVWSNDV 488
            .|.|...||.......||| |.|....:....|.:::|||:|||.||.|:||.:..::.::.:.|
Mouse   638 VPVPVESHAQRVANFALGMRISAKEVMNPVTGEPIQIRVGIHTGPVLAGVVGDKMPRYCLFGDTV 702

  Fly   489 SLANKMESSGKPEQVHISQETSSFLGDAYY--LEEGE-EVFGH---RTYFVVGRRRDFT------ 541
            :.|::|||.|.|.:||:|......|.:..:  :..|| ||.|.   .|||:: |..:.|
Mouse   703 NTASRMESHGLPNKVHLSPTAHRALENKGFEIVTRGEIEVKGKGKMTTYFLI-RNLNATEVEIMG 766

  Fly   542 RTNSLSPSMPANATGSSLLLPGAHGASLSQSATNVSAVQPNVPPASPVGQLSSSL-----NPSPV 601
            |.::|:....|:...:.:..|.|..:::......|.    |..||..:|..|.:.     :|:|:
Mouse   767 RPSALADGKEASTPRNQVKKPRAVLSNMDHHQQQVY----NSDPADVLGTASRTASVKGKHPTPL 827

  Fly   602  601
            Mouse   828  827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	65/216 (30%)
		Guanylate_cyc	361..535	CDD:278633	62/180 (34%)
		CYCc	1362..1556	CDD:214485
		Guanylate_cyc	1388..1575	CDD:278633
Gucy1b2	XP_011243363.2	HNOB	115..276	CDD:400167
		HNOBA	380..566	CDD:400168	7/28 (25%)
		Guanylate_cyc	572..754	CDD:306677	64/208 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810