Protein Alignment Ac13E and gcy-34

DIOPT Version :9

• Sequence 1: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_506319.1
• Gene: gcy-34 / 191656
• WormBaseID: WBGene00001554
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 653
• Identity: 133/653 - (20%)
• Similarity: 242/653 - (37%)
• Gaps: 170/653 - (26%)

  Fly  1097 TPRYNTYID------IFVGIAVYLCISVSLFLMTQNTVSPSFRL-----WVTLFSCFTG------ 1144
            :|....::|      .|:...||          ..|...||||.     ...:...|||
 Worm    91 SPNLKGFLDNLDSLHYFIDHVVY----------KANLRGPSFRCEENPDGTLMLHYFTGRPGLYH 145

  Fly  1145 -----IQVFALFLF-----------TRQMCRRQSGSNVSNR----FRSKSTTSEDLERDERGAAP 1189
                 ::..|..:|           |::.....:|..|...    .::......|.:.....|..
 Worm   146 IVKGVVKEVAKLVFNLDISLVVQGRTQRSVHMNNGERVEEHVIFLIKNVEEPRRDSDTSTTSALT 210

  Fly  1190 GGRPHF-ESCADRI---FEAISSWYPWHI-----CLAVLMAMPVLLIIANFLLL-DLEQLEAFEY 1244
            ...|.| |...|.:   .:..|...|:|.     |..|.....:...|.|.||. ....|..||
 Worm   211 SVEPDFGEIIDDNLKVSLQDFSRALPYHFVLDESCRLVQCGDELYNHIPNELLQPGTPILRIFE- 274

  Fly  1245 HYGFLIFVCIVHFCNFTQLNCWVRNVLAFLAALCFIGIAVSQLMVYSHN-RSDQQQDQEASNFIQ 1308
                         .|..|:.....|:..|:.|:..:.:..|.|.....| .:.::::||.....:
 Worm   275 -------------INRPQIPLDFENICNFINAVFVLQVKTSPLRKKHMNAMTKEEREQEVEAMEE 326

  Fly  1309 EI---KWFQDYHVEIYLDLLL------ILVL----VWFLNREFEIGYRLTFYGNAVANQDKV--- 1357
            |:   :..|..|:::...:::      |:.|    |..:|...:.|.|||......|.:|.:
 Worm   327 EVESNELTQGCHLKLKGQMMMLSTKKHIIYLCSPYVTSINELMQFGMRLTAMPLHDATRDLILLN 391

  Fly  1358 ------------------RVQNM-------KNQADMLLHNIIPKHVAEHLKNTAKYSENHHNIAI 1397
                              :::.|       :.:.|.:|.:::|:.:|:.|.:........:...:
 Worm   392 QQRLSDVEVNLQLEANNEQLETMTHELEVERQKTDSILKDMLPRKIAKQLLSGEHLEPCEYEATV 456

  Fly  1398 IFASIVNFNEMYDESYLGGKEFLRVLNELIGDFDELLSRPEFRAVEKIKTIGSTFMAASGLDPSH 1462
            :|..:..|.::.  .....|..:::|||:....|.::   ..|.|.|::|:..::|..||: |.:
 Worm   457 MFCDLPAFQQII--PVCQPKNIVKLLNEVFFKLDRIV---VLRGVYKVETVSDSYMTVSGI-PDY 515

  Fly  1463 RGTGDEHIHTLMEFSIAM----QEVVDAFNKDLLEFNLILRIGMNIGDVTAGVIGTSKLYYDIWG 1523
            .   .||...:...::.|    :.|:|..||.    ..:||||::.|.:.|||:||....|.::|
 Worm   516 T---SEHAENMCHVALGMMWEARSVMDPVNKT----PFLLRIGLHSGTIIAGVVGTKMPRYCLFG 573

  Fly  1524 DAVNVASRMDSTGLPNRIQVGKDCLPFL------TNRYEFEPRGSVYVKGKDHMEVFLYTTRRDN 1582
            :.|.:||:|:|.|:..:||    |..:.      |.|:||.|||.:.|||:..:|.:..
 Worm   574 ETVTLASQMESLGVAGKIQ----CSSWTYSKAMETGRFEFSPRGRINVKGRGDVETYFL------ 628

  Fly  1583 PLDDDEADKVEQLGTKK-----MEHEGRDEDV--VQGEQQAEDKDEEEEEEEED-----DDLHSS 1635
                       ....||     .:|| ||.:|  ::|.::.|...|..:..:.|     :..||:
 Worm   629 -----------MRSLKKSIWEITDHE-RDVNVNSIEGYEELEIFIENAQTVKHDGHPKANQNHSA 681

  Fly  1636 ETT 1638
            ..|
 Worm   682 TCT 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485
		Guanylate_cyc	361..535	CDD:278633
		CYCc	1362..1556	CDD:214485	51/210 (24%)
		Guanylate_cyc	1388..1575	CDD:278633	54/196 (28%)
gcy-34	NP_506319.1	HNOB	3..167	CDD:285002	15/85 (18%)
		HNOBA	224..441	CDD:285003	40/230 (17%)
		CYCc	421..609	CDD:214485	50/204 (25%)
		Guanylate_cyc	453..629	CDD:278633	54/209 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810