Protein Alignment Ac13E and gcy-33

DIOPT Version :9

• Sequence 1: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_001256392.1
• Gene: gcy-33 / 179644
• WormBaseID: WBGene00001553
• Length: 947
• Species: Caenorhabditis elegans
• Alignment Length: 562
• Identity: 120/562 - (21%)
• Similarity: 230/562 - (40%)
• Gaps: 135/562 - (24%)

  Fly   276 LIMNLVRMRGTFMKVGQNLLVRRQL--EMEKQLKE------KMIHSVMPPKVADMLLNEGGPSGL 332
            :||..::...|...:.:|...|.::  ||.:::.|      .::..:||.:||..::..|...
 Worm   368 IIMATIQKSDTLKTMLENEKRRSEVLTEMTREISEAKKTARTLLTQMMPYEVAQTMMRSGSVD-- 430

  Fly   333 DAGGLPPESHYMRPRASNDVKSLFRPFHMHSMENVSILFADIVGFTRMSSTKTAEQLVEILNDLF 397
                                       |..:.|.|||.|..:..|:::|....|.::|.:||.::
 Worm   431 ---------------------------HCEAFECVSIGFIRVCDFSKISLFIEAFEVVNLLNTIY 468

  Fly   398 ERFDDLCSLSGCEKISTLGDCYYCVSGCPEPRADH-----AICCVEMGLGMIDAMRCFDAQRHEG 457
            ...|.:....|..|:.|:|:.|...:|||. |.|:     :.||:|    |:..::.|:.|.|:.
 Worm   469 SHLDSIVDTHGVYKVETIGESYMISAGCPY-RDDYDAEMVSDCCLE----MVSHIKSFEYQSHDA 528

  Fly   458 VK---MRVGVHTGTVLCGIVGTRRVKFDVWSNDVSLANKMESSGK-PEQVHISQETSSFL----G 514
            ||   ::.|:.||.|:.|:||.|..::.::.:.|:.|::||||.: |..:.|.|.|...:    .
 Worm   529 VKKVLIKCGIFTGPVVGGVVGVRTPRYCLFGDTVNTASRMESSNQTPMTIQIGQRTKDRVEKQAS 593

  Fly   515 DAYYLEEGEEVF-----GHRTYFV---VGRRRDFTRTNSLSPSMPANATGSSLLLPGAHGASLSQ 571
            .|:.::....||     ..|.|.:   .||.| :.:::.|...|.|....:..||...:....|.
 Worm   594 GAFRIKPKGNVFVKGKGDMRVYEIEKKKGRAR-YKKSDPLRKKMVAEKKEAEELLDEDNEGHRSS 657

  Fly   572 SATNVSAVQPNVPPASPVGQLS-SSLNPSPVLSMRPRLTS-----LSMKMRKK-------SQSRD 623
            :.:.:|..:.....:|..|.|| |.|..:..::....|||     |.:.|:.:       |.|..
 Worm   658 ALSRMSLGESIDSSSSRRGSLSGSQLELNKTIAQTIELTSKASAALDLNMQDENNRPPTWSASHS 722

  Fly   624 RDVERGIIHPAAAGIPPVIVVRERPKIIITTK---------SLPGSLDSDEQPPVSPPLLPPANP 679
            :|:.:    |.          :...||.:.::         .:..|.|||.:.|         .|
 Worm   723 QDIRK----PR----------KTESKITLNSRLSSSDLAVSRVETSKDSDGETP---------RP 764

  Fly   680 PAAETRSKIKLKVWKIPRFLKRFEDLTNRSSCGGSSSAGHLDKEREREREKEKEELHQHNQLNPE 744
            .::|.:...::          |.|.|..             :||.||..::|.:::.:..:.:..
 Worm   765 TSSELKEVNRI----------REEALAQ-------------EKEEERTTKEENQKIEEVGEDHVS 806

  Fly   745 ETLAFMDNQMQNG-NGCGYQQLPVLVESNHRTQTLDIPAARP 785
            |..:.:|:::.:| |...:.|:|  .:|........:|:|.|
 Worm   807 EATSLLDSEVSHGDNNISFSQMP--SDSIPHEDRTSLPSATP 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	58/234 (25%)
		Guanylate_cyc	361..535	CDD:278633	54/194 (28%)
		CYCc	1362..1556	CDD:214485
		Guanylate_cyc	1388..1575	CDD:278633
gcy-33	NP_001256392.1	HNOB	2..164	CDD:377902
		HNOBA	204..423	CDD:369471	12/54 (22%)
		CYCc	402..598	CDD:214485	57/229 (25%)
		COG5134	<595..744	CDD:227463	32/163 (20%)
		TDA11	<710..>898	CDD:293689	31/185 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910