Protein Alignment Ac13E and gucy1a2

DIOPT Version :9

• Sequence 1: NP_001259575.1
• Gene: Ac13E / 32485
• FlyBaseID: FBgn0022710
• Length: 1703
• Species: Drosophila melanogaster
• Sequence 2: NP_001120379.1
• Gene: gucy1a2 / 100145454
• XenbaseID: XB-GENE-1011801
• Length: 712
• Species: Xenopus tropicalis
• Alignment Length: 405
• Identity: 103/405 - (25%)
• Similarity: 156/405 - (38%)
• Gaps: 121/405 - (29%)

  Fly   247 MEANGD-----PSNRILIL---------RIMA---HLS---VH-------LVGVHV-----LIMN 279
            ||..|.     .|:.||.|         .:|.   |||   :|       |||...     |...
 Frog   384 MEVKGQMIYVPESSSILFLGSPRVDKLDELMGRGLHLSDIPIHDATRDVILVGEQAKAQDGLKKR 448

  Fly   280 LVRMRGTFMKVGQNLLVRRQLEMEKQLKEKMIHSVMPPKVADMLLNEGGPSGLDAGGLPPESHYM 344
            :.:::.|..|..|      .||.||:....:::|:.|..||..|. ||
 Frog   449 MDKLKATLEKTHQ------ALEEEKKKTVDLLYSIFPGDVAQQLW-EG----------------- 489

  Fly   345 RPRASNDVKSLFRPFHMHSMENVSILFADIVGFTRMSSTKTAEQLVEILNDLFERFDDLCSLSGC 409
                    ||:    .....::|::||:||||||.:.:..|..|::.:||:|:.|||..|.....
 Frog   490 --------KSV----QARKFDDVTMLFSDIVGFTAVCAQCTPMQVISMLNELYTRFDYQCGFLDI 542

  Fly   410 EKISTLGDCYYCVSGCPEPRADHAICCVEMGLGMIDAMRCFDAQRHEGVKMRVGVHTGTVLCGIV 474
            .|:.|:||.|...:|.......||.....|.|.|::............:|||:|:|:|:||.|:|
 Frog   543 YKVETIGDAYCVAAGLLRQSNSHAKPIALMALKMMELSEEVLTPDGRPIKMRIGIHSGSVLAGVV 607

  Fly   475 GTRRVKFDVWSNDVSLANKMESSGKPEQVHISQETSSFLGDAYYLEEGEEVFGHRTYFVVGRRRD 539
            |.|..::.::.|:|:||:|.||...|.::::|..|...|.|            ...:..|.|.|:
 Frog   608 GVRMPRYCLFGNNVTLASKFESGSHPRRINVSPTTYQLLKD------------EANFHFVPRSRE 660

  Fly   540 FTRTNSLSPSMPANATGSSLLLPGAHGASLSQSATNVSAVQPNVPPASPVGQLSSSLNPSPVLSM 604
                 .|..:.|....|....|....|..           ||
 Frog   661 -----ELPDNFPKEIPGICYFLEADSGQK-----------QP----------------------- 686

  Fly   605 RPRLTSLSMKMRKKS 619
            :|.||  |::|||.|
 Frog   687 KPSLT--SVRMRKVS 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	64/215 (30%)
		Guanylate_cyc	361..535	CDD:278633	53/173 (31%)
		CYCc	1362..1556	CDD:214485
		Guanylate_cyc	1388..1575	CDD:278633
gucy1a2	NP_001120379.1	Pap_E4	30..>86	CDD:367150
		HNOB	<132..248	CDD:377902
		HNOBA	296..486	CDD:369471	27/107 (25%)
		Guanylate_cyc	492..679	CDD:306677	60/207 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910