Protein Alignment Gmap and Gmap

DIOPT Version :10

• Sequence 1: NP_001356946.1
• Gene: Gmap / 32483
• FlyBaseID: FBgn0027287
• Length: 1401
• Species: Drosophila melanogaster
• Sequence 2: XP_061504213.1
• Gene: Gmap / 1272826
• VectorBaseID: AGAMI1_009751
• Length: 1247
• Species: Anopheles gambiae
• Alignment Length: 1504
• Identity: 471/1504 - (31%)
• Similarity: 718/1504 - (47%)
• Gaps: 363/1504 - (24%)

  Fly     1 MSW--LNSSLSQLKGQLTNLAQEVLAETAGPGDLEYEGHQAGGASVQDAEQQAKTALELLAETQE 63
            |||  ||.||:::||.:|:..|||.||                ..:.:.|.....|.| |:..:|
Mosquito     1 MSWLKLNDSLNKVKGSITSFTQEVFAE----------------GIIGEDEADENPARE-LSVARE 48

  Fly    64 QKEQLDKRCEEKDREIAALRRELAKSKQKQESQLAASTSATREP---------------QLQNEE 113
            :.:||...|..:|:|||.||:::.:.:|.|    ..|:|.|::|               .|..|:
Mosquito    49 KIDQLTDLCATQDQEIATLRKQIVEFQQLQ----LPSSSGTQQPGPSAKPSSGESKPSGSLGPEQ 109

  Fly   114 ------------PNVEDSWCWEPDGGDEKGATGAGSGDSASRDKESGLVDI--------ALGNDD 158
                        ..:||||.|:||  :...:|.:.|....:....||..|:        |..:|.
Mosquito   110 HVGTSITTTTVTSTLEDSWFWDPD--NNISSTSSSSKKDDNESPSSGPTDLTTIPLEAPASESDI 172

  Fly   159 VVRLNNRIAE-LEQL--------------------NEQLNVSLEELDSQHELAMRDVLEHKTQLA 202
            :.||..::.| |:||                    |.:||.::||||.|||:.:.:::..|..|.
Mosquito   173 IERLQRQLNEKLQQLKKQQLENALLNEKLGQVSGENRELNENIEELDRQHEVVLENLVASKRDLQ 237

  Fly   203 GQVASLKQLQADRLVEHELSNARQQKQLDELRQTSSAAKKQQEELQRRVEQQEAEL-------IE 260
            .|...|:.....:..|.|.:..:.|.:.:.|.||.:...:..|:|:....:..|||       :|
Mosquito   238 AQCGRLEAELKAKATESETALQQLQARFERLEQTHAQTCQDNEKLRTETAKLTAELERIVCENVE 302

  Fly   261 MQDLLDKRRQDTAELIERVRVAETERERLLKDLEETRQAKEKKTSESSSNSSSTGKHSEDEFIVV 325
            ....|:::.|:..:  ||. .|:...:.|.:::||.||    :|::.::           ||:|
Mosquito   303 AVAALERQLQEQRD--ERA-TADELCQTLREEIEELRQ----RTADEAA-----------EFVV- 348

  Fly   326 RQADATGSGSASGSDRDPDADVTSPPSKEKLRDRLVSLESQISELTLANTQLQDAQLEKQLSINM 390
              |..|....|      |.|::.:  ..|:||..|..:.::..     |.|...|:|::...|..
Mosquito   349 --AVPTPEQPA------PSAELVA--ELEQLRQALEDVRTERD-----NLQKLTAELDRSEHIGQ 398

  Fly   391 LGEQLVELEKRLRLSEAEKEQLQVNLQLRLQQLTVQNQELKLHAEAEQEGHAQNLEEQLGDLRED 455
            |..::.||:..||                  .:.:.|       ..:.||.|:..:|:|..||::
Mosquito   399 LEREIGELQNELR------------------SVIIDN-------SVQLEGKAKEYDEKLATLRQE 438

  Fly   456 NQRLRQELKTSIAQAKFRQAIAEEKQEITDLDDADSEYGTFELDKLRALLQAEIEDRLDSSFPQQ 520
            ||.||:.|             |.|:.........|...|    :.:|....      ||.:.|.:
Mosquito   439 NQTLRESL-------------ANEQTAKQSEPGPDGRVG----EIIRQFFD------LDLNEPDR 480

  Fly   521 KLERAWNALKDRWHRLDLVEQRLVD---------VQNQQLVSEHEKKTLEADISQYILQCDELMK 576
            ..||. .|.:|...:|..:|::|:|         .:|.::  :|:|.||.||:.||..:|..|||
Mosquito   481 LAERL-QATRDLDAKLAALERKLIDAGKEINFLKAENSRI--QHDKDTLTADLMQYEKECASLMK 542

  Fly   577 NNDLLLNELDKYKRNKLETIEEHHEETIVQLEAQLEEARQKLELASLSSQQQMETHLISSPEKTP 641
            |||.||.||:..|.||||||.|:.|::||.||.||::|.
Mosquito   543 NNDRLLEELENVKCNKLETINENAEDSIVVLEKQLDDAH-------------------------- 581

  Fly   642 VDSELLAKMEQKEQEYLQLQEQLAFAKTELDKRNKLLERNGEQLTKQQQQNQADQKKLEELSQLR 706
                                           :.|:.||                       .:.|
Mosquito   582 -------------------------------RLNRTLE-----------------------EEYR 592

  Fly   707 ETLQRRDEDLKELEEQLSAVRQDLDEKSIQMKISQDQHKLQLANLQNQLQADQEKLRELLQLQDK 771
            |..::.:|.|:|.||.|::|.        .::.|:.:.|.:...|:..| |:..|.|:  :|.::
Mosquito   593 EAHRKLEEVLEEKEELLTSVS--------TLETSESEGKARTLALERSL-AEVRKERD--ELTER 646

  Fly   772 LEQQKEL--MEVDQNQQITIIKKELAETTNQLSECQERLTVKEAQLAEIQQQLQEVNEERTRLQE 834
            |:|.::.  .|.:|      ::.||.....||:...|    ..|.|....||||..:.|..|..|
Mosquito   647 LQQLRDAGGQEAEQ------LRTELTSMQGQLTTINE----DHASLVRKLQQLQHTSSENVRTWE 701

  Fly   835 QLLTKEQESGLDSELAKRNQELEDQLLAKEQQLQLNQAELEKLQETLRVNEEQLLAKEEQLHAKE 899
                           .|.|:        ..|.|:..::|||:.:|:....|:|     :||.|:.
Mosquito   702 ---------------GKLNE--------MRQLLEARESELEQARESTAAAEQQ-----QQLAAES 738

  Fly   900 SQLQSLESQLQGQLAADESQQLQQTIDGLGQEKNELIKVLQQKHQENTQYYAEIQRLQPFEQ--- 961
            .:.::            |.:|.::.::.|.|:|..|::::..||.|:.||:||||||....|
Mosquito   739 ERYRA------------ELEQQREALESLTQQKENLVQLVTTKHNESVQYHAEIQRLNQLLQAET 791

  Fly   962 -----------QVKELVKEREKLQDQVGFLKEKSDILTTNLLTEQTNQRLLQQQQAESQEQQAST 1015
                       .::|.:.|.|:|.||:.||:|||||||.||:|||:|||...|::....||:...
Mosquito   792 ERAAPACPDCPALREKLHEHERLTDQIQFLREKSDILTANLMTEQSNQRQALQEKQLLVEQRDGL 856

  Fly  1016 LRDLERLRAHLLEIEELHTQETVELQRDLEESRSRQAILEQQVSKSSTAYTSASIRANQQAETLQ 1080
            .|||||||.|||||||.||||||||||..:::|.:.|.||::|.:|:.|.|||||||||||||||
Mosquito   857 QRDLERLRQHLLEIEEAHTQETVELQRRYDDTRQQLASLEREVKQSTNALTSASIRANQQAETLQ 921

  Fly  1081 AQHALLQQQRDELLAKLGQYEDRELKQQAALTNLQCALEQFQNDKDHDIEMATQRIRREMQAQLD 1145
            ||:.||.||||||.|:|...:||:.|.|||||||||||||||.:::.|||:||..||.|::....
Mosquito   922 AQYQLLLQQRDELGARLSAADDRDQKNQAALTNLQCALEQFQMNRERDIELATGSIRSELEQART 986

  Fly  1146 RQGQLQLEMSGLQQQLAEANQGLRAAARLSDQLEAGQQTIAVLRDEVESLKEANGQLEQRLSSSE 1210
            |:..|:..:..:|||||:|..||.||||:|||||..|.|:|.|:.|:....|....|||||..:|
Mosquito   987 REEALKDTLKQVQQQLADAKTGLLAAARISDQLEISQVTVASLKAELTKRDERYAALEQRLQETE 1051

  Fly  1211 SSQTDKIDKSLIKSLLIGYVVSGHAGDKQQVLRMISSVLDFNAQEADKVGLNKQ-----QSSWLG 1270
            :||.||::|:|:|:|:|||.|:.:|.|:||::::|||||..:..|..||||:.:     ...||.
Mosquito  1052 ASQADKVEKTLVKNLVIGYAVAPNASDRQQIMKLISSVLTMDQNECTKVGLHHRGTVGGTGGWLN 1116

  Fly  1271 AILGGGSATASAAGSSRGNENLVQAFVQFLEQESQPQAQSRPTLLSMTGQMDGVTSASATTSTAA 1335
            :|||||.  :..||::...|:|.:|||:|||:||.|:|.:..:||::      |||.:|.|.|.:
Mosquito  1117 SILGGGG--SGEAGANYNKESLTEAFVKFLEKESAPRATASSSLLNI------VTSPAAATGTTS 1173

  Fly  1336 TSG---HLPQASSSFSPATPAASQQDPAAPRTPPVGGSPQ--------LLAMGSNEFAPTRNSSS 1389
            :.|   ...|...|.:.:|...:.........||...|.|        ::.|....|||.|:|||
Mosquito  1174 SVGEQQQQQQQQQSMATSTTTVTSVGSNLITAPPASSSVQPILVPEAAMMMMQQPGFAPPRSSSS 1238

  Fly  1390 ILKDILSDS 1398
            |||||||||
Mosquito  1239 ILKDILSDS 1247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmap	NP_001356946.1	SMC_prok_B	169..973	CDD:274008	199/855 (23%)
		Smc	<645..>1195	CDD:440809	203/565 (36%)
Gmap	XP_061504213.1	None