DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6324 and Ogfr

DIOPT Version :9

Sequence 1:	NP_001285273.1	Gene:	CG6324 / 32481	FlyBaseID:	FBgn0030647	Length:	923	Species:	Drosophila melanogaster
Sequence 2:	NP_113550.3	Gene:	Ogfr / 72075	MGIID:	1919325	Length:	633	Species:	Mus musculus

Alignment Length:	394	Identity:	82/394 - (20%)
Similarity:	140/394 - (35%)	Gaps:	123/394 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 GKSQKVMEQQPSKI-KPM-------KPSEPMNPIQPVNLKGQINPIGPVNPMDQKIIKDSVNPMG 111
            |...|:...:|..| :|:       |...|.:|.|....:|:....|          :|.....|
Mouse   277 GPRDKLRRFRPQTISRPLMGLGQADKDEGPGDPSQEAGTQGRTCGSG----------RDLSGDSG 331

  Fly   112 QIKPMNPMCQRNSMASVNPY-------GQIHPKGPVNPNPNGQMKHMGPMNLMEPGNPNGQINSM 169
            ..:.:       |:.|..|.       .|.|.....:|..:.:.|..|......||.|:.|  .:
Mouse   332 TAEDL-------SLLSAKPQDVGTLDGDQRHEAKSPSPKESKKRKLEGNRQEQVPGEPDPQ--GV 387

  Fly   170 SQMNPMGQINIMSQMNLMDQINLMSQMNLMGEPVNPNVQMKPMETFPNGQINPMEPMNP------ 228
            |::..:.                   :||.|..::|..|            .|.|...|
Mouse   388 SEVEKIA-------------------LNLEGCALSPTSQ------------EPREAEQPCLVARV 421

  Fly   229 ---------------------NGQMNSMSSMNPMGQMNPMDQMNLISQMNLMGGPVNPNGQMNPM 272
                                 |.|:.: |:::|.....|..|.:       ..||.:|..|:.|.
Mouse   422 ANEVRKRRKVEEGAEGDGVASNTQVQA-SALSPTPSECPESQKD-------GNGPEDPKSQVGPE 478

  Fly   273 EPGNPNGQINSMSQI---NPMGQINRPVNPNGQMNRMEPGNPNGQMNSMSQMNLMRGPVNPNGQM 334
            :|.:..|..:..||:   :|..|:. |.:|.||   :||.:|.||:          ||.:|.||:
Mouse   479 DPKSQVGPEDPKSQVGPEDPKSQVG-PEDPKGQ---VEPEDPKGQV----------GPEDPKGQV 529

  Fly   335 N-MNSYGQMNPMEPRNPNGQMNAMSQMNLMRGPVNPNGQMN-MNSYGQMNPMEPRNPNGQMNAMS 397
            . .:..||:.|.:|::..|..:..||:.    |.:|..|:. .:...|:.|.:|::..|..:..|
Mouse   530 GPEDPKGQVGPEDPKSQVGPEDPKSQVE----PEDPKSQVEPEDPKSQVEPEDPKSQVGPEDPQS 590

  Fly   398 QMNP 401
            |:.|
Mouse   591 QVGP 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6324	NP_001285273.1	Med15	115..>449	CDD:255446	69/326 (21%)
Ogfr	NP_113550.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44
		OGFr_N	76..283	CDD:282512	2/5 (40%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255	257..286		2/8 (25%)
		PHA03169	284..>548	CDD:223003	67/335 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	287..390		24/121 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	404..633		53/229 (23%)
		14 X approximate tandem repeats	467..592		40/142 (28%)
		VCX_VCY	472..620	CDD:291884	39/141 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910