DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg14 and Alg14

DIOPT Version :9

Sequence 1:	NP_573031.1	Gene:	Alg14 / 32479	FlyBaseID:	FBgn0030645	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	XP_006501962.1	Gene:	Alg14 / 66789	MGIID:	1914039	Length:	222	Species:	Mus musculus

Alignment Length:	214	Identity:	87/214 - (40%)
Similarity:	119/214 - (55%)	Gaps:	39/214 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TTSSPHPT--------YVILGS-----GGHTAEMCRLTQALLQQTDIEQTEKYQPIRLILANSDS 53
            |...||..        .::.||     ||||.|:.||..:|        :..|.|...::|.||.
Mouse    24 TVLGPHHVTPRESLRLLIVAGSVFLFLGGHTTEILRLVGSL--------SNAYSPRHYVIAESDE 80

  Fly    54 TSERQFRQVLPQAAQRA------EFVK-----VPRSRDVGQSWLSSIFTSLWALLWSCYLVWRDR 107
            .|.::...:  :...||      |:.|     :||||:|.||||||:||:.:::.:|..||.|.:
Mouse    81 MSAKKIHSL--EELSRAQNDSTTEYPKYHLHRIPRSREVRQSWLSSVFTTFYSMWFSFPLVLRIK 143

  Fly   108 PQLILCNGPGTCVPFCYAAYLWRLLGRLPSHSRIVFVESFCRVETLSLSGRLLLPLADLFVVHWP 172
            |.|:||||||||||.|.:|.|..:||  .....||:|||.||||||||||::|..|:|.|:|.||
Mouse   144 PDLVLCNGPGTCVPICVSALLLGILG--VKKVIIVYVESICRVETLSLSGKILRHLSDYFIVQWP 206

  Fly   173 ALATRYLDKKNVRYFGRIL 191
            .|..:|  .|:| |.|||:
Mouse   207 TLKEKY--PKSV-YLGRIV 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg14	NP_573031.1	Alg14	9..190	CDD:285823	82/204 (40%)
Alg14	XP_006501962.1	Alg14	39..221	CDD:370045	81/186 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836257
Domainoid	1	1.000	139	1.000	Domainoid score	I4795
eggNOG	1	0.900	-	-		E1_KOG3339
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49751
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4478
Isobase	1	0.950	-	0	Normalized mean entropy	S2002
OMA	1	1.010	-	-		QHG56795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005186
OrthoInspector	1	1.000	-	-		oto92020
orthoMCL	1	0.900	-	-		OOG6_102531
Panther	1	1.100	-	-	LDO	PTHR12154
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R39
SonicParanoid	1	1.000	-	-		X3700
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740