DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg14 and ALG14

DIOPT Version :9

Sequence 1:	NP_573031.1	Gene:	Alg14 / 32479	FlyBaseID:	FBgn0030645	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	NP_659425.1	Gene:	ALG14 / 199857	HGNCID:	28287	Length:	216	Species:	Homo sapiens

Alignment Length:	189	Identity:	80/189 - (42%)
Similarity:	111/189 - (58%)	Gaps:	21/189 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VILGSGGHTAEMCRLTQALLQQTDIEQTEKYQPIRLILANSDSTSERQFRQVLPQAAQRAE---- 71
            |:.||||||.|:.||..:|        :..|.|...::|::|..|..:........|.|..
Human    41 VVAGSGGHTTEILRLLGSL--------SNAYSPRHYVIADTDEMSANKINSFELDRADRDPSNMY 97

  Fly    72 ----FVKVPRSRDVGQSWLSSIFTSLWALLWSCYLVWRDRPQLILCNGPGTCVPFCYAAYLWRLL 132
                ..::||||:|.|||.|::||:|.::..|..|:.|.:|.|:||||||||||.|.:|.|..:|
Human    98 TKYYIHRIPRSREVQQSWPSTVFTTLHSMWLSFPLIHRVKPDLVLCNGPGTCVPICVSALLLGIL 162

  Fly   133 GRLPSHSRIVFVESFCRVETLSLSGRLLLPLADLFVVHWPALATRYLDKKNVRYFGRIL 191
            |  .....||:|||.|||||||:||::|..|:|.|:|.||||..:|  .|:| |.|||:
Human   163 G--IKKVIIVYVESICRVETLSMSGKILFHLSDYFIVQWPALKEKY--PKSV-YLGRIV 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg14	NP_573031.1	Alg14	9..190	CDD:285823	78/186 (42%)
ALG14	NP_659425.1	Alg14	39..215	CDD:285823	78/186 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146155
Domainoid	1	1.000	133	1.000	Domainoid score	I5099
eggNOG	1	0.900	-	-		E1_KOG3339
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49751
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4577
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56795
OrthoDB	1	1.010	-	-		D1449763at2759
OrthoFinder	1	1.000	-	-		FOG0005186
OrthoInspector	1	1.000	-	-		oto88449
orthoMCL	1	0.900	-	-		OOG6_102531
Panther	1	1.100	-	-	LDO	PTHR12154
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R39
SonicParanoid	1	1.000	-	-		X3700
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800