DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Grip128 and Tubgcp6

DIOPT Version :9

Sequence 1:	NP_573030.2	Gene:	Grip128 / 32478	FlyBaseID:	FBgn0026433	Length:	1092	Species:	Drosophila melanogaster
Sequence 2:	NP_001102218.2	Gene:	Tubgcp6 / 362980	RGDID:	1307743	Length:	1763	Species:	Rattus norvegicus

Alignment Length:	451	Identity:	94/451 - (20%)
Similarity:	174/451 - (38%)	Gaps:	96/451 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   589 KRNMGMEDDLLLVEIFNKLQSCPLYQLLLEHALESGETQDLLCSVNTLSEMLTSNNEIQLPSLHD 653
            :||...||          |..|          |.|...:|.|.|....||        ::||...
  Rat  1314 RRNRDAED----------LSPC----------LPSSPQEDTLPSSPGPSE--------EVPSTEA 1350

  Fly   654 ELFTQFFAQLKVYCGADNTD-YEDEPEPDKDYEDLTVCNRQGIRNHEL---FAIFTQPLVEQRLE 714
            | ..:.:.:.:.|. ||.|. |..|..|| .||.::......:.:|.|   ||....|.|:..::
  Rat  1351 E-EARRWGKEQAYL-ADLTKLYRLEQYPD-SYESMSEPPMAHLVHHMLPRAFAFPVDPQVQSAVD 1412

  Fly   715 R---QRERLKSNPVLMANILKRLERSTCLQLKSELPEALREILRRRQWLANEYAIRAYCKETQVA 776
            .   |...|.:.||||       :||....|.:.:.            |.|:.|:..:..|..:.
  Rat  1413 ESAVQLSELLTLPVLM-------KRSLMAPLAAHVS------------LVNKAAVDYFFVELHLE 1458

  Fly   777 EKMRFLRHTMLLEKYYLFVPYYNALFVRM-------EKNNSWALGSVLTSKLCAVL---LPHYPQ 831
            .....|||.:|:|.........:.||.::       |..|...|.|:|:..|...|   .||...
  Rat  1459 THFEALRHFLLMEDGEFAQSLSDLLFEKLGAGQTPGELLNPLVLNSILSKALQYSLHGDTPHATN 1523

  Fly   832 LAHYLHVKLISQINSNSIKVYEALEAIELDFERPMAMHQWYILTPAHMQDYNSVWRLMLKVKWAV 896
            |:..|  |.:.::.:.:..  :.|..:||.::....::  .::|.:.:..|:.::..:|::|..:
  Rat  1524 LSFAL--KYLPEVFAPNAP--DVLSCLELRYKVDWPLN--IVITESCLNKYSGIFSFLLQLKLMM 1582

  Fly   897 WKLENMQF-LRRARFNPCAPLDLIGLT-----IRRLEIVRFWLIFLINNLHAHIMEAVSR----Q 951
            |.|:::.| |:|..        |:..|     .|:|::.:..:...:..:..:|...:..    :
  Rat  1583 WTLKDICFHLKRTA--------LVSHTAGSVQFRQLQLFKHEMQHFVKVIQGYIANQILHVSWCE 1639

  Fly   952 FELRIGECKNVRELRIMHDEHLAWLKTHCMLTDEFKAFRVALDQIFHLV-----YVLDMEW 1007
            |..|:....::.|::..|.|:|.......:||::.......:..||.||     .::...|
  Rat  1640 FRARLAVVGDLEEIQRAHAEYLHRAVFRGLLTEKAAPVMNIIHSIFSLVLKFRSQLISQNW 1700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Grip128	NP_573030.2	Spc97_Spc98	373..>580	CDD:282045
Tubgcp6	NP_001102218.2	GCP_N_terminal	352..612	CDD:407574
		TPH	628..>805	CDD:404709
		DUF4573	1044..1199	CDD:405774
		Spc97_Spc98	1460..1760	CDD:398000	49/255 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110079at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010