Protein Alignment Grip128 and Tubgcp5

DIOPT Version :9

• Sequence 1: NP_573030.2
• Gene: Grip128 / 32478
• FlyBaseID: FBgn0026433
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: NP_666302.2
• Gene: Tubgcp5 / 233276
• MGIID: 2178836
• Length: 1024
• Species: Mus musculus
• Alignment Length: 1185
• Identity: 211/1185 - (17%)
• Similarity: 415/1185 - (35%)
• Gaps: 405/1185 - (34%)

  Fly    72 EVKRNLDDLAERFRAEGMASFGESIKDLAIRYL-AMDENQQQFNPNPGWQMLELLFRIADRPVQK 135
            :|::.::.:.|:|......:...|.|.|...:| |...:.::...:..:.:|.||..::|.|
Mouse    60 KVEKTIEGIYEKFTIHSDLNKAASWKRLTKEFLNASLPSTEKIKTDAHYSILSLLLCLSDSP--- 121

  Fly   136 IRLNREFMEQRRLSIINSMEEAERQAQIEEQAKLEAAKNTSETEVDWAALLSE-------DFLDP 193
              .|..::            |..|:.::|:           :.:.||...|.|       ..:|.
Mouse   122 --SNSNYV------------ETPREKEVEK-----------KDDFDWGKYLMEGEEIGLGPNIDT 161

  Fly   194 PEDDSSDSLSDWSEESDC-DSTTTL-KPDENIGVSRSLLEMARVYEQAMMAVVPTGSVNKTYMPP 256
            |         :|||:||. |:...| :.|..|.|.|:.||
Mouse   162 P---------NWSEDSDDEDAQQPLSREDSGIQVDRTPLE------------------------- 192

  Fly   257 EQSVIRSYDFRIMKPTVLSLNNLKGSHLRRSKLLQLPPPQ---PPRPFTQYWQSGNTDTLFRKIH 318
            ||.                 :|.||.            ||   ...|.::.|...:.      :|
Mouse   193 EQD-----------------HNRKGG------------PQVCWEDEPDSRSWLEQHV------VH 222

  Fly   319 SHWWCQDVHLNALPSSAKPLDNFAVSYVQFLNHNARGLLALPVPK---TITEPCLLREILFMF-- 378
            .:|..:...   :|.||....|.|..:.|.|..:.    .|.||.   .:||..::||.|::.
Mouse   223 QYWTTRRFR---IPHSAHLHSNLAAVWDQHLYSSD----PLYVPDDRVVVTETQVIRETLWLLSG 280

  Fly   379 VRPASCCFFEFDKATRRITVRDNVSICTVTASTMQNFLLFDVVPALEDMMELRHIIDTHTLHFHG 443
            |:.    .|.|.....::|||:|:.:..:|.|.::: :|..:....:.:..|:..||
Mouse   281 VKK----MFIFQLIDGKVTVRNNIIVTHLTHSCLRS-VLEQIAAYGQVVFRLQEFID-------- 332

  Fly   444 VKTTYTVEFFAYGLRDLVQ---PICQLLIAYEDRVNKDPAKN-------------TLIRFTIEFR 492
                   |...:....|..   ||              |.|.             .|.::.|.|:
Mouse   333 -------EVMGHSSESLPPGNGPI--------------PKKQPDAPFRTYQAFMWALYKYFINFK 376

  Fly   493 EHFSQL------------------RLLRELAEDVILDK----GPAH--------IRSAYLLSRLY 527
            |..:.:                  :|...||:..:|||    |.|.        :|:::||:.||
Mouse   377 EELTDIEKCVISSDTTITLAIVVNKLAPRLAQLKVLDKVFSTGVAEVPPDTRNVVRASHLLNTLY 441

  Fly   528 KHTLLQVPH----QKLATALLFI----SLKRYCIIIDGWWRRAALEDHLREFIV----------- 573
            | .:|:..:    .:...:|||.    :::.|...:|.|.....|.|..||||:
Mouse   442 K-AILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGHLWDGAREFIIQRNKNVPVNHR 505

  Fly   574 EFCY----------------------------EEDANTRSH--------VRKRNMGMEDDLLLVE 602
            :|.|                            ::..::|.|        |.|:.:.....:.|::
Mouse   506 DFWYATYTLYSVSEKTENEDKVSDSASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLK 570

  Fly   603 IFNKLQ--SC----------PLYQLLLEH---ALESGE-------TQDLLCSVNTLSEMLTSNNE 645
            ..|..:  :|          .||.|.||.   .|:.||       .:|.....|.:.....:...
Mouse   571 NLNCAEGPACQAAARDAERKSLYTLFLESIQLRLQHGEDSAPHIVNEDQTTKENLIKMQSIAERH 635

  Fly   646 IQLPSLHDELFTQFFAQLKVYCGADNTDYEDEPE-----PDKDYEDLTVCNRQGIRNHELFAIFT 705
            ::|..:||.|....||:|.:    :.:|:.::..     .|:..|.:| |        :.|.:..
Mouse   636 LELDDIHDPLLAINFARLYL----EQSDFHEKFAGGDICVDRSSESVT-C--------QTFELTL 687

  Fly   706 QPLVEQRLERQRERLKSNPVLMANILKRLERSTCLQLKSELPEALREILRRRQWLANEYAIRAYC 770
            :..:...:::|...      ...|:::.|:|
Mouse   688 RSCLYPHIDKQYLH------CCGNLMQTLKR---------------------------------- 712

  Fly   771 KETQVAEKMRFLRHTMLLEKYYLFVPYYNALFVRMEKNNSWALGSVLTSKLCAVLLPHYPQLAHY 835
             :.::.|.::.:|:..|:|.......:|.::|.::.:..:|...|.|..:|...:...||:.:..
Mouse   713 -DFRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSLR 776

  Fly   836 LHVKLISQINSNSIKV-YEALEAIELDFERPMAMHQW---YILTPAHMQDYNSVWRLMLKVKWAV 896
            |.:. ...:::...|: ...|:.:.|.::.|     |   .:::....:.||.|:.|:|::|||.
Mouse   777 LSIS-FENVDTTKKKLPVHILDGLTLSYKVP-----WPVDIVISVECQKIYNQVFLLLLQIKWAK 835

  Fly   897 WKLENMQF---------------LRR-----ARFNPCAPLDLIGLTIRRLEIVRFWLIFLINNLH 941
            :.|:.:.|               :.|     ::|.|  |.:.:...|.|:.::|..|:..:|:||
Mouse   836 YSLDVLLFGELGNAAERSQAKEDIPRDQDTPSQFGP--PKESLRQQIHRMFLLRVKLMHFVNSLH 898

  Fly   942 AHIM----EAVSRQFELRIGECKNVRELRIMHDEHLAWLKTHCMLTDEFKAFRVALDQIFHLVYV 1002
            .:||    .:...:|:.::.|.|::.:|..:|..:|:.:...|:|.::....:.|:.::.:|..:
Mouse   899 NYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLALM 963

  Fly  1003 LDMEWTTCASCMHDHDALCLDVTISDDGIDDSETQRRSLEYLALNQVAEIELTYIRCHQMLADIL 1067
            ....|                              :..|....:..:.::|..:..||..|..||
Mouse   964 FAEGW------------------------------QAGLGAWQMESIEKMESDFKNCHMFLVTIL 998

  Fly  1068 NTLVHQNDHGFLSAL 1082
            |..|.:.....|.:|
Mouse   999 NKAVCRGSFPHLESL 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grip128	NP_573030.2	Spc97_Spc98	373..>580	CDD:282045	54/301 (18%)
Tubgcp5	NP_666302.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..203		20/112 (18%)
		Spc97_Spc98	273..942	CDD:282045	135/765 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	523..545		0/21 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	853..873		3/21 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837134
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4344
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H14172
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5287
Isobase	1	0.950	-	1.056642	Normalized mean entropy	S8357
OMA	1	1.010	-	-		QHG58662
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005643
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_105210
Panther	1	1.100	-	-	LDO	PTHR19302
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5727
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870