DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6299 and PLEKHA3

DIOPT Version :9

Sequence 1:NP_001285269.1 Gene:CG6299 / 32475 FlyBaseID:FBgn0030641 Length:205 Species:Drosophila melanogaster
Sequence 2:NP_061964.3 Gene:PLEKHA3 / 65977 HGNCID:14338 Length:300 Species:Homo sapiens


Alignment Length:49 Identity:13/49 - (26%)
Similarity:22/49 - (44%) Gaps:16/49 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 KPYH-------GFIVQSTIKIIYSWVPTRSQLLGQGVAQAENIEVLTSF 179
            :|.|       |.:..:||       |..|:|:.:  .|:|:.:.|.||
Human   259 RPVHCSKNTLNGDLASATI-------PEESRLMAK--KQSESEDTLPSF 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6299NP_001285269.1 GLTP 32..163 CDD:285880 7/31 (23%)
PLEKHA3NP_061964.3 PH_FAPP1_FAPP2 1..100 CDD:269951
Interaction with SACM1L. /evidence=ECO:0000269|PubMed:30659099 1..100
Interaction with VAPA and VAPB. /evidence=ECO:0000269|PubMed:30659099 97..300 13/49 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 197..300 13/49 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165148091
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm40747
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.840

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