DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6299 and Plekha8

DIOPT Version :9

Sequence 1:	NP_001285269.1	Gene:	CG6299 / 32475	FlyBaseID:	FBgn0030641	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	NP_001157833.1	Gene:	Plekha8 / 231999	MGIID:	2681164	Length:	519	Species:	Mus musculus

Alignment Length:	188	Identity:	52/188 - (27%)
Similarity:	93/188 - (49%)	Gaps:	19/188 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LETQAFLDASKEIVTVIESFG-KLFTPVISDMNGNINKLTKAYGADVVKYQYLEDLIVLNVNVD- 91
            :.|:|||.:...:|.|::..| .:|.||..|:.|||.|:.:.|..:..::..|:.:::..|..|
Mouse   330 IPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADV 394

  Fly    92 ----DFAANALLWLKRGLQLICTFFENIYNDAQAKEALKQHLQDAYERTLKPYHGFIVQSTIKII 152
                :.|..|||||||||:.:..|...:.|   .::.::..|.:||.:||:.:||::|:....:.
Mouse   395 AQVRNSATEALLWLKRGLKFLKGFLTEVKN---GEKDIQTALNNAYGKTLRQHHGWVVRGVFALA 456

  Fly   153 YSWVPTRSQLLG-----QGVAQAENIEV-----LTSFLPRMRAHLDSIDALLKAHNLD 200
            ....|:....:.     :|..|.|....     |:.:||.|...|..:|.|.:.|.|:
Mouse   457 LRAAPSYEDFVAALTIKEGDHQKEAFSAGMQRDLSLYLPAMEKQLAILDTLYEIHGLE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6299	NP_001285269.1	GLTP	32..163	CDD:285880	39/136 (29%)
Plekha8	NP_001157833.1	PH_FAPP1_FAPP2	1..100	CDD:269951
		PH	1..93	CDD:278594
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..302
		Glycolipid transfer protein homology domain	330..473		40/145 (28%)
		GLTP	333..470	CDD:285880	39/139 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838182
Domainoid	1	1.000	75	1.000	Domainoid score	I9030
eggNOG	1	0.900	-	-		E1_KOG3221
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42819
orthoMCL	1	0.900	-	-		OOG6_101874
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4235
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.670