DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6299 and plekha8

DIOPT Version :9

Sequence 1:	NP_001285269.1	Gene:	CG6299 / 32475	FlyBaseID:	FBgn0030641	Length:	205	Species:	Drosophila melanogaster
Sequence 2:	XP_002932833.3	Gene:	plekha8 / 100489403	XenbaseID:	XB-GENE-949914	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	198	Identity:	58/198 - (29%)
Similarity:	97/198 - (48%)	Gaps:	29/198 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DTADKLETQAFLDASKEIVTVIESFGK-LFTPVISDMNGNINKLTKAYGADVVKYQYLEDLIVLN 87
            :..:.:.|:.|||:...||.|::..|. :|.||..|..|||.|:.:.|.....::..|:.:::..
Frog   353 EDGEGIPTERFLDSCYAIVPVLDKLGSTVFAPVKMDFVGNIKKINQKYITSKEEFTTLQKIVLHE 417

  Fly    88 VN-----VDDFAANALLWLKRGLQLICTFFENIYNDAQAKEALKQHLQDAYERTLKPYHGFIVQS 147
            ||     |.:.|..|||||||||:.:..|...:.|   .::.::..|.:||.:||:.|||::|:.
Frog   418 VNANVTQVRNSATEALLWLKRGLKFLYEFLSEVRN---GEKNIQTALSNAYGKTLRQYHGWVVRG 479

  Fly   148 TIKIIYSWVPTRSQLLGQGVAQAENIEV---------------LTSFLPRMRAHLDSIDALLKAH 197
            ...:.....||.     :|.|.|.:||.               |..:||.|:..|:.:|.|.:.|
Frog   480 VFALALRAAPTY-----EGFATALSIEEGEGNKEGFFNAMKRDLNIYLPAMQKQLNILDTLYEEH 539

  Fly   198 NLD 200
            .|:
Frog   540 GLE 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6299	NP_001285269.1	GLTP	32..163	CDD:285880	43/136 (32%)
plekha8	XP_002932833.3	PH_FAPP1_FAPP2	18..117	CDD:269951
plekha8	XP_002932833.3	GLTP	361..494	CDD:400867	43/140 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I8792
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47929
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4235
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940