DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ahcy and HOG1

DIOPT Version :9

Sequence 1:	NP_001285268.1	Gene:	Ahcy / 32471	FlyBaseID:	FBgn0014455	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_193130.1	Gene:	HOG1 / 827028	AraportID:	AT4G13940	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	473	Identity:	271/473 - (57%)
Similarity:	331/473 - (69%)	Gaps:	47/473 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YKVADISLAEWGRKAIIIAENEMPGLMACRKKYGPSKPLKGARITGCLHMTVQTAVLIETLVELG 70
            |||.|:|.|::||..:.:||.|||||||||.::|||:|.|||||||.||||:|||||||||..||
plant    14 YKVKDMSQADFGRLELELAEVEMPGLMACRTEFGPSQPFKGARITGSLHMTIQTAVLIETLTALG 78

  Fly    71 AQVQWSSCNIFSTQDNAAAAIAATGVPVYAWKGETDEEYMWCIEQTLVF-PDGQPLNMILDDGGD 134
            |:|:|.|||||||||:||||||.....|:||||||.:||.||.|:.|.: |.|.| ::|:|||||
plant    79 AEVRWCSCNIFSTQDHAAAAIARDSAAVFAWKGETLQEYWWCTERALDWGPGGGP-DLIVDDGGD 142

  Fly   135 LTNLVHE-----------------------------------------KFPQYLKNIKGLSEETT 158
            .|.|:||                                         |:.:..:.:.|:|||||
plant   143 ATLLIHEGVKAEEIFEKTGQVPDPTSTDNPEFQIVLSIIKEGLQVDPKKYHKMKERLVGVSEETT 207

  Fly   159 TGVHNLYKMFKEGRLGVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVCCVAGYGD 223
            |||..||:|.:.|.|..|||||||||||||||||||||.||.||:.|||||||||||..:.||||
plant   208 TGVKRLYQMQQNGTLLFPAINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMIAGKVAVICGYGD 272

  Fly   224 VGKGCAQALKGFGGRVIVTEVDPINALQAAMEGYEVTTMEEASKEASIFVTTTGCRDIITSVHLQ 288
            ||||||.|:|..|.||||||:|||.||||.|||.:|.|:|:...||.|||||||.:|||...|::
plant   273 VGKGCAAAMKTAGARVIVTEIDPICALQALMEGLQVLTLEDVVSEADIFVTTTGNKDIIMVDHMR 337

  Fly   289 QMPDDAIVCNIGHFDIEIDVDWLNA-NAKEKVNVKPQVDRYTMQSGK-HIILLAEGRLVNLGCAH 351
            :|.::||||||||||.|||:..|.. ...:::.:|||.||:.....| .||:||||||:|||||.
plant   338 KMKNNAIVCNIGHFDNEIDMLGLETYPGVKRITIKPQTDRWVFPETKAGIIVLAEGRLMNLGCAT 402

  Fly   352 GHPSFVMSNSFTNQVLAQIELWTK--SDKYAVGVHVLPKILDEEVASLHLEKLGVKLTKLTEKQA 414
            ||||||||.||||||:||:|||.:  |.||...|:||||.|||:||.|||.|||.:||||::.|:
plant   403 GHPSFVMSCSFTNQVIAQLELWNEKASGKYEKKVYVLPKHLDEKVALLHLGKLGARLTKLSKDQS 467

  Fly   415 TYLGVSQTGPFKPDHYRY 432
            .|:.:...||:||.||||
plant   468 DYVSIPIEGPYKPPHYRY 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ahcy	NP_001285268.1	PRK05476	1..426	CDD:235488	265/465 (57%)
Ahcy	NP_001285268.1	AdoHcyase	6..431	CDD:283003	268/470 (57%)
HOG1	NP_193130.1	PLN02494	9..485	CDD:178111	269/471 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0499
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H554
Inparanoid	1	1.050	504	1.000	Inparanoid score	I310
OMA	1	1.010	-	-		QHG60675
OrthoDB	1	1.010	-	-		D371693at2759
OrthoFinder	1	1.000	-	-		FOG0004180
OrthoInspector	1	1.000	-	-		otm3004
orthoMCL	1	0.900	-	-		OOG6_100715
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2929
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740