Protein Alignment Ahcy and Ahcy

DIOPT Version :10

• Sequence 1: NP_511164.2
• Gene: Ahcy / 32471
• FlyBaseID: FBgn0014455
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_057870.3
• Gene: Ahcy / 269378
• MGIID: 87968
• Length: 432
• Species: Mus musculus
• Alignment Length: 430
• Identity: 346/430 - (80%)
• Similarity: 373/430 - (86%)
• Gaps: 1/430 - (0%)

  Fly     3 KPSYKVADISLAEWGRKAIIIAENEMPGLMACRKKYGPSKPLKGARITGCLHMTVQTAVLIETLV 67
            |..||||||.||.|||||:.||||||||||..|:.|..|||||||||.|||||||:|||||||||
Mouse     4 KLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLV 68

  Fly    68 ELGAQVQWSSCNIFSTQDNAAAAIAATGVPVYAWKGETDEEYMWCIEQTLVFPDGQPLNMILDDG 132
            .|||:|:|||||||||||:||||||..|:||:||||||||||:|||||||.|.|| |||||||||
Mouse    69 ALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDG-PLNMILDDG 132

  Fly   133 GDLTNLVHEKFPQYLKNIKGLSEETTTGVHNLYKMFKEGRLGVPAINVNDSVTKSKFDNLYGCRE 197
            ||||||:|.|:||.|..|:|:||||||||||||||...|.|.|||||||||||||||||||||||
Mouse   133 GDLTNLIHTKYPQLLSGIRGISEETTTGVHNLYKMMSNGILKVPAINVNDSVTKSKFDNLYGCRE 197

  Fly   198 SLIDGIKRATDVMIAGKVCCVAGYGDVGKGCAQALKGFGGRVIVTEVDPINALQAAMEGYEVTTM 262
            ||||||||||||||||||..|||||||||||||||:|||.|||:||:||||||||||||||||||
Mouse   198 SLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTM 262

  Fly   263 EEASKEASIFVTTTGCRDIITSVHLQQMPDDAIVCNIGHFDIEIDVDWLNANAKEKVNVKPQVDR 327
            :||.||.:||||||||.|||...|.:||.||||||||||||:||||.|||.||.||||:||||||
Mouse   263 DEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDR 327

  Fly   328 YTMQSGKHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKSDKYAVGVHVLPKILDE 392
            |.:::|:.|||||||||||||||.|||||||||||||||:|||||||..|||.||||.|||.|||
Mouse   328 YWLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDE 392

  Fly   393 EVASLHLEKLGVKLTKLTEKQATYLGVSQTGPFKPDHYRY 432
            .||..||.||.|||||||||||.|||:...||||||||||
Mouse   393 AVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ahcy	NP_511164.2	AdoHcyase	6..431	CDD:461594	342/424 (81%)
Ahcy	NP_057870.3	AdoHcyase	8..431	CDD:214963	340/422 (81%)
		NAD binding. /evidence=ECO:0000250|UniProtKB:P10760	183..350		138/166 (83%)