Protein Alignment Scamp and SCAMP1

DIOPT Version :9

• Sequence 1: NP_001259572.1
• Gene: Scamp / 32470
• FlyBaseID: FBgn0040285
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_004857.4
• Gene: SCAMP1 / 9522
• HGNCID: 10563
• Length: 338
• Species: Homo sapiens
• Alignment Length: 354
• Identity: 157/354 - (44%)
• Similarity: 217/354 - (61%)
• Gaps: 39/354 - (11%)

  Fly     4 SGLDENPFGEPNLDNPFADPAIQQ-ARRLQSGAALVSLEDYNPFEEQAKPQ----LQINSTNT-A 62
            |..|.|||.:|:|:|||.||::.| .|.:..|     |::||||.:...|.    ...|..|| .
Human     2 SDFDSNPFADPDLNNPFKDPSVTQVTRNVPPG-----LDEYNPFSDSRTPPPGGVKMPNVPNTQP 61

  Fly    63 AVVQPLSQNIPPPQTSSLGASAPSTSIQITSE------ELQRRQEELDRKAAELDRREQQLQGNV 121
            |:::|..::  |..|            ||..|      ||.:|||||:||||||||||:::| |:
Human    62 AIMKPTEEH--PAYT------------QIAKEHALAQAELLKRQEELERKAAELDRREREMQ-NL 111

  Fly   122 PQ---LNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLI-LLF 182
            .|   .|||||||.||.|.|||||||.|:||.||||.||.:||:|:|:.:||..|:.|.|. ...
Human   112 SQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLAWFCV 176

  Fly   183 HAGEFETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFNK 247
            .:.....|.|:|.:.:||:|.|:|||:||.|.|||:||||.|.||||:|..|....::||.||:.
Human   177 DSARAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHN 241

  Fly   248 MGYCGFITAIGQFDGQASGIIVGILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQAEF 312
            .|.||:|:::   .|....|.|||:::.:|..|||.||.:::|..|:|.:||:||||..|||.||
Human   242 WGNCGWISSL---TGLNQNIPVGIMMIIIAALFTASAVISLVMFKKVHGLYRTTGASFEKAQQEF 303

  Fly   313 TTEFLRNQHVQEAASSAVNTAINSQFNNS 341
            .|..:.|:.||.||::|.:||.:|...|:
Human   304 ATGVMSNKTVQTAAANAASTAASSAAQNA 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Scamp	NP_001259572.1	SCAMP	125..301	CDD:282056	86/176 (49%)
SCAMP1	NP_004857.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64		25/66 (38%)
		SCAMP	117..292	CDD:309320	86/177 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141103
Domainoid	1	1.000	185	1.000	Domainoid score	I3381
eggNOG	1	0.900	-	-		E1_KOG3088
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37975
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2913
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51893
OrthoDB	1	1.010	-	-		D544579at33208
OrthoFinder	1	1.000	-	-		FOG0000703
OrthoInspector	1	1.000	-	-		otm40287
orthoMCL	1	0.900	-	-		OOG6_101583
Panther	1	1.100	-	-	O	PTHR10687
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3229
SonicParanoid	1	1.000	-	-		X309
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.840