DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scamp and scamp1

DIOPT Version :9

Sequence 1:	NP_001259572.1	Gene:	Scamp / 32470	FlyBaseID:	FBgn0040285	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_991255.1	Gene:	scamp1 / 402992	ZFINID:	ZDB-GENE-040426-1803	Length:	338	Species:	Danio rerio

Alignment Length:	346	Identity:	154/346 - (44%)
Similarity:	212/346 - (61%)	Gaps:	24/346 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SGLDENPFGEPNLDNPFADPAIQQARRLQSGAALVSLEDYNPFEEQ------AKPQLQINSTNT- 61
            |..|.|||.:|:..|||.||::.|..|    .|...||:||||.:.      :.|:....:|||
Zfish     2 SDFDSNPFADPDFSNPFQDPSVTQVTR----TAPPGLEEYNPFTDTKPVPPGSAPKSVPPTTNTQ 62

  Fly    62 AAVVQPLSQNIPPPQTSSLGASAPSTSIQITSEELQRRQEELDRKAAELDRREQQLQ---GNVPQ 123
            .|:::|..:  ||..|.|  ...|..|  ....||.||||||:||||||||||:::|   .:..:
Zfish    63 PAIMKPTEE--PPAYTQS--QQTPDQS--RAQAELLRRQEELERKAAELDRREREMQSLNASGGR 121

  Fly   124 LNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLI-LLFHAGEF 187
            .|||||||:.|.|.||||.|..|:||.|:||.||.:||:|:|:|.||.||:.|.|. ....|...
Zfish   122 KNNWPPLPEKFPVGPCFYHDISVDIPVEYQKTVKIMYYLWMFHTGTLFANIFGCLSWFCVDASRG 186

  Fly   188 ETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFNKMGYCG 252
            ..|.||:.:.|||:|.|:|||:||.|.|||:||||.|.||||:|..|....::||:|....|..|
Zfish   187 VDFGLAMLWFMLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFGVHVLQAIGITGWGASG 251

  Fly   253 FITAIGQFDGQASGIIVGILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQAEFTTEFL 317
            :|:|:   .|..:.|.|||:::.:|..|||.||.:::|..|:|::||:||||..|||.||.|..:
Zfish   252 WISAL---TGLNTSIPVGIIMILIAALFTASAVISLIMFKKVHALYRTTGASFEKAQQEFATGVM 313

  Fly   318 RNQHVQEAASSAVNTAINSQF 338
            .|:.||.||::|.::|....|
Zfish   314 ANKTVQTAAANAASSAARGAF 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scamp	NP_001259572.1	SCAMP	125..301	CDD:282056	85/176 (48%)
scamp1	NP_991255.1	SCAMP	122..297	CDD:282056	85/177 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573975
Domainoid	1	1.000	177	1.000	Domainoid score	I3542
eggNOG	1	0.900	-	-		E1_KOG3088
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37975
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2960
OMA	1	1.010	-	-		QHG51893
OrthoDB	1	1.010	-	-		D544579at33208
OrthoFinder	1	1.000	-	-		FOG0000703
OrthoInspector	1	1.000	-	-		otm24852
orthoMCL	1	0.900	-	-		OOG6_101583
Panther	1	1.100	-	-	O	PTHR10687
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3229
SonicParanoid	1	1.000	-	-		X309
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800