DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scamp and SCAMP5

DIOPT Version :9

Sequence 1:	NP_001259572.1	Gene:	Scamp / 32470	FlyBaseID:	FBgn0040285	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	XP_006720483.1	Gene:	SCAMP5 / 192683	HGNCID:	30386	Length:	253	Species:	Homo sapiens

Alignment Length:	225	Identity:	100/225 - (44%)
Similarity:	139/225 - (61%)	Gaps:	9/225 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 GNV--PQLNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLILL 181
            ||:  .::||:||||....:|||||||||.:|||:...:.|||||:|:..::||..|::|.|..|
Human    16 GNIMAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLAWL 80

  Fly   182 FHAGEFETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFN 246
            ...|....|.||..:.:||:|.||||||||.||||:.||||:||.|||.:..|.:.||:||||..
Human    81 IGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIP 145

  Fly   247 KMGYCGFITAIGQFDGQASGIIVG--ILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQ 309
            ..|.||:|..|..|     |..:|  :::|.....||.:||.:.:.::.:|..||.:|.|.:|||
Human   146 GWGVCGWIATISFF-----GTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQ 205

  Fly   310 AEFTTEFLRNQHVQEAASSAVNTAINSQFN 339
            .|:||...:|.|||:||.:|...|.....|
Human   206 EEWTTGAWKNPHVQQAAQNAAMGAAQGAMN 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scamp	NP_001259572.1	SCAMP	125..301	CDD:282056	81/177 (46%)
SCAMP5	XP_006720483.1	SCAMP	24..197	CDD:282056	81/177 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141107
Domainoid	1	1.000	185	1.000	Domainoid score	I3381
eggNOG	1	0.900	-	-		E1_KOG3088
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D544579at33208
OrthoFinder	1	1.000	-	-		FOG0000703
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X309
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.710