DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scamp and scm-1

DIOPT Version :9

Sequence 1:	NP_001259572.1	Gene:	Scamp / 32470	FlyBaseID:	FBgn0040285	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_490911.1	Gene:	scm-1 / 171756	WormBaseID:	WBGene00004743	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	352	Identity:	132/352 - (37%)
Similarity:	185/352 - (52%)	Gaps:	51/352 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DNPFADP---------AIQQARRLQSGAALVSLEDYNPFEEQAKPQLQINSTNTAAVVQPLSQNI 72
            |||||||         |...|.:..||.. :..||:|||..:|      ..:|    .||.:..
Worm     3 DNPFADPFSAPPPPPAAAAAASKPTSGGT-IETEDFNPFANRA------GGSN----AQPTTHQ- 55

  Fly    73 PPPQTSSLGASAPSTSIQITSEELQRRQEELDRKAAELDRREQQL-----------------QGN 120
               .|.|||..:..     ..:||.|:|::|:|:|.||..||::|                 |.|
Worm    56 ---STGSLGNKSAG-----MDDELFRKQQDLERRAQELRMREEELDRRQRSAAGGNNLNTNAQNN 112

  Fly   121 VPQLNNWPPLPDNFCVKPCFYQDFEVEIPPEFQKLVKRLYYIWIFYTMTLLANVIGGLI-LLFHA 184
            .|:.:||||||....::||||||.|||||.:|||.|...||:::.|.:.|:.||:..|. ::|..
Worm   113 APRPHNWPPLPTIIPIEPCFYQDIEVEIPVQFQKTVTFAYYVFLMYVLALVVNVLASLFYMIFAG 177

  Fly   185 GEFETFFLAIFYTMLFSPASYVCWFRPAYKAFRNDSSFNFMVFFFIYFFQTLYSIVQAVGFNKMG 249
            |.....|||.....||||.|::.||||.|||||||||||||||||:.||..:::.||.:|.:...
Worm   178 GSIGQLFLACIQLALFSPCSFLFWFRPVYKAFRNDSSFNFMVFFFVLFFHCIFTFVQTLGLSNYA 242

  Fly   250 YCGFITAIGQFDGQASGIIVGILLLNVAFCFTAVAVANVLMITKIHSIYRSTGASMAKAQAEFTT 314
             ||:|.|:..|:   ..:.:.:|:|..|..||......|..:.|:|.:||..|.|:.||:.|||.
Worm   243 -CGWINALDTFN---VSVPIALLMLISAITFTVALTGMVTALVKVHRLYRGAGFSIDKARQEFTN 303

  Fly   315 EFLRNQHVQEAASSAVNTAINSQFNNS 341
            ..:.:..||.|..:|...|..:.||.:
Worm   304 GVMSDAGVQRATQAATQAAAGAAFNQA 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scamp	NP_001259572.1	SCAMP	125..301	CDD:282056	79/176 (45%)
scm-1	NP_490911.1	SCAMP	116..289	CDD:282056	78/176 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166994
Domainoid	1	1.000	166	1.000	Domainoid score	I2364
eggNOG	1	0.900	-	-		E1_KOG3088
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37975
Inparanoid	1	1.050	223	1.000	Inparanoid score	I2255
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51893
OrthoDB	1	1.010	-	-		D544579at33208
OrthoFinder	1	1.000	-	-		FOG0000703
OrthoInspector	1	1.000	-	-		oto17562
orthoMCL	1	0.900	-	-		OOG6_101583
Panther	1	1.100	-	-	LDO	PTHR10687
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3229
SonicParanoid	1	1.000	-	-		X309
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800