DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cngl and KAT1

DIOPT Version :9

Sequence 1:	NP_001245691.1	Gene:	Cngl / 32468	FlyBaseID:	FBgn0263257	Length:	1970	Species:	Drosophila melanogaster
Sequence 2:	NP_199436.1	Gene:	KAT1 / 834666	AraportID:	AT5G46240	Length:	677	Species:	Arabidopsis thaliana

Alignment Length:	695	Identity:	150/695 - (21%)
Similarity:	288/695 - (41%)	Gaps:	122/695 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 SFLKRFSTRQIPETQETVEDTGSESA--SGDVDKSVKRRRRYLQK-RRSVVNPDENFYFYWLMML 249
            :|.:||.      .:|...||..:|:  |.|:..|:..|.....| |:.:::|....|..|.|.|
plant     8 NFFERFC------VEEYNIDTIKQSSFLSADLLPSLGARINQSTKLRKHIISPFNPRYRAWEMWL 66

  Fly   250 TVCVLYNLWTLIVRQSFPELQQSVPTFWLICDSMTDVVFILDIIVQLRTGYLEQG--LMVYDDRK 312
            .:.|:|:.|....:.:|...::..   ..|.|::.:..|.:|||:.....||:..  |:|...:|
plant    67 VLLVIYSAWICPFQFAFITYKKDA---IFIIDNIVNGFFAIDIILTFFVAYLDSHSYLLVDSPKK 128

  Fly   313 LACHYVHSRDFIFDMIALIPLDLLQL-------KMGTH--PLLRFTR-------FFKVYRSVRFY 361
            :|..|: |..|.||:.:..|...|.|       ::|..  .:||..|       |.::.:.:||.
plant   129 IAIRYL-STWFAFDVCSTAPFQPLSLLFNYNGSELGFRILSMLRLWRLRRVSSLFARLEKDIRFN 192

  Fly   362 YIVESRTVWPNLW-RVVNLIHILLILAHWFGCFYFLLSEA-EGFQGDWVYPYRPG-DYATLTRKY 423
            |          .| |...||.:.|...|..|||.:|:::. ...:..|:....|. ..|:|..:|
plant   193 Y----------FWIRCTKLISVTLFAIHCAGCFNYLIADRYPNPRKTWIGAVYPNFKEASLWNRY 247

  Fly   424 LGSLYWSTLTLTT--IGDLPTPETNAEYIFTIVSYLIGVFIFATIVGQVGNVITNRNANRLEFER 486
            :.:||||..||||  .||... |...|.:|.|...:..:.:.|.::|.:.|::.:..:....|..
plant   248 VTALYWSITTLTTTGYGDFHA-ENPREMLFDIFFMMFNLGLTAYLIGNMTNLVVHWTSRTRTFRD 311

  Fly   487 LLDGAKTYMRHHKVPGGMKRRVLRWYDYSWSRGRIQGGGDINTALGLLPDKLKTELALHVNLSVL 551
            .:..|..:...:::|..::.::|......:....::....:|.    ||..:::.:|.::...::
plant   312 SVRAASEFASRNQLPHDIQDQMLSHICLKFKTEGLKQQETLNN----LPKAIRSSIANYLFFPIV 372

  Fly   552 KKVTIFQECQPEFLHDLVLKMKAYIFTPGDSICRKGEVAREMFIIADGILEVL-------SETGK 609
            ..:.:||.....||..||..:.|..|.|.:.|..:.|...:::|:..|.::..       ...||
plant   373 HNIYLFQGVSRNFLFQLVSDIDAEYFPPKEDIILQNEAPTDLYILVSGAVDFTVYVDGHDQFQGK 437

  Fly   610 VLTTMKAGDFFGEIGILNLDGLNKRTADVRSVGYSELFSLSREDVLAAMKDYPDAQEILQTLGRK 674
            .:    .|:.|||:|:|.   ...:...||:...|::..:||..:::||..:.|...::
plant   438 AV----IGETFGEVGVLY---YRPQPFTVRTTELSQILRISRTSLMSAMHAHADDGRVI------ 489

  Fly   675 RLMEVRCVNKKYAKAQSDKEAAAYAAAHPHHHQSHHQGQVHQS----------------DSSENS 723
                   :|..:.|.:..:..|.     ...:.|.|:.:..:|                |.:..:
plant   490 -------MNNLFMKLRGQQSIAI-----DDSNTSGHENRDFKSMGWEEWRDSRKDGYGLDVTNPT 542

  Fly   724 ASKKIVDKL-KHDVKGFRNVLK-----KSRTSRKSDESLEMQPLHNTSPR-----GSKILLKRMS 777
            :...::|.: |.|.:..:.:||     :::..|.|.|:......:::|.:     .|..::|...
plant   543 SDTALMDAIHKEDTEMVKKILKEQKIERAKVERSSSETAGRSYANDSSKKDPYCSSSNQIIKPCK 607

  Fly   778 RVRSDEKDAD---SAEAKDELHDKTPSPIGAGLPLLQRLRLLKEK 819
            |   :||...   .:|:|:......||.|.      :.|||..||
plant   608 R---EEKRVTIHMMSESKNGKLILLPSSIE------ELLRLASEK 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cngl	NP_001245691.1	Ion_trans	260..481	CDD:278921	61/243 (25%)
		Ion_trans_2	382..476	CDD:285168	28/97 (29%)
		Crp	550..>680	CDD:223736	29/136 (21%)
		CAP_ED	556..668	CDD:237999	29/118 (25%)
KAT1	NP_199436.1	PLN03192	26..677	CDD:215625	144/671 (21%)
		Ion_trans_2	230..301	CDD:285168	22/71 (31%)
		CAP_ED	377..490	CDD:237999	29/132 (22%)
		KHA	611..674	CDD:288667	11/39 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2706
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870