DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cngl and KAT3

DIOPT Version :9

Sequence 1:	NP_001245691.1	Gene:	Cngl / 32468	FlyBaseID:	FBgn0263257	Length:	1970	Species:	Drosophila melanogaster
Sequence 2:	NP_194991.1	Gene:	KAT3 / 829400	AraportID:	AT4G32650	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	111/537 - (20%)
Similarity:	214/537 - (39%)	Gaps:	102/537 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 YFYWLMMLTVCVLYNLWTLIVRQSFPELQQSVPTFWLICDSMTDVVFILDIIVQLRTGYLEQG-- 304
            |..|.:.|.:.|.|:.|..:...:|.:..:..   .|..|.:.|..|.:|||:.....||:..
plant    86 YRLWELFLVILVGYSAWASLFELAFEKAAEGA---LLTIDLVVDFFFAVDIILTFFVSYLDNTTY 147

  Fly   305 LMVYDDRKLACHYVHSRDFIFDMIALIPLDLLQLKM----------GTHPLLRFTR-------FF 352
            |.|.|.:.:|..|:.|..|:.|:.:.:|:..:...:          |...|||..|       |.
plant   148 LNVTDHKLIAKRYLKSVAFVMDVASTLPIQFIYKTITGDVGRGQAFGFLNLLRLWRLRRVAELFK 212

  Fly   353 KVYRSVRFYYIVESRTVWPNLWRVVNLIHILLILAHWFGCFYFLLSEAEGFQGDWV---YPYRPG 414
            ::.:...|.|.|         .||:.|:.:.:...|..||..:           |:   || ||.
plant   213 RLEKDAHFNYFV---------IRVIKLLCVTIFWIHLAGCILY-----------WIAYHYP-RPT 256

  Fly   415 D-----------YATLTRKYLGSLYWSTLTLTTI--GDLPTPETNAEYIFTIVSYLIGVFIFATI 466
            |           ..::...|..|:|||.:||||:  |||....:. |..|.:...|..:.:.:.|
plant   257 DTWIGSQVEDFKERSVWLGYTYSMYWSIVTLTTVGYGDLHAVNSR-EKTFNMFYMLFNIGLTSYI 320

  Fly   467 VGQVGNVITNRNANRLEFERLLDGAKTYMRHHKVPGGMKRRVLRWYDYSWSRGRIQGGGDINTAL 531
            :|.:.|::.:...........::....|...:::|..|:.::|......:....::.    ...|
plant   321 IGIMTNLVVHGALRTFAMRSAINDILRYTSKNRLPDTMREQMLAHMQLKFKTAELRQ----EEVL 381

  Fly   532 GLLPDKLKTELALHVNLSVLKKVTIFQECQPEFLHDLVLKMKAYIFTPGDSICRKGEVAREMFII 596
            ..||..:::.:..|:..|::::..:|:......|..||.:::|..|.|...|..:.|:..:.::|
plant   382 QDLPKAIRSSINQHLFRSIIEEAYLFKGFPEGLLVQLVSQIQAEYFPPKMEIILQNEIPTDFYVI 446

  Fly   597 ADGILEVLSETG---KVLTTMKAGDFFGEIGIL-NLDG----LNKRTADVRSVGYSELFSL--SR 651
            ..|.:::::..|   :||..:..|...||||:: |:..    ..:|.:.|..:|:.:...:  |.
plant   447 VSGGVDIIASKGVSEQVLAKLGPGSMAGEIGVVFNIPQPFTVRTRRLSQVIRIGHHKFKEMVQSD 511

  Fly   652 EDVLAAM-----------------KDYPDAQEILQTLGRKRLMEVRCVNKKYAKAQSDKEAAAYA 699
            .||.|.|                 |:.|..:::|.. ...::.|.  |..:.....:|:|....:
plant   512 NDVDAKMIIANFMTYLKGLNDELKKEIPFLRDLLDD-ADAQVQET--VQSEETPQSNDEEIVTVS 573

  Fly   700 AAHPHHHQSHHQGQVHQ 716
                    .|..||:.:
plant   574 --------RHENGQIEE 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cngl	NP_001245691.1	Ion_trans	260..481	CDD:278921	58/255 (23%)
		Ion_trans_2	382..476	CDD:285168	27/109 (25%)
		Crp	550..>680	CDD:223736	32/156 (21%)
		CAP_ED	556..668	CDD:237999	30/138 (22%)
KAT3	NP_194991.1	PLN03192	51..>532	CDD:215625	101/474 (21%)
KAT3	NP_194991.1	KHA	590..661	CDD:403134
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2706
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.880