DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cngl and CNGC14

DIOPT Version :9

Sequence 1:	NP_001245691.1	Gene:	Cngl / 32468	FlyBaseID:	FBgn0263257	Length:	1970	Species:	Drosophila melanogaster
Sequence 2:	NP_001324934.1	Gene:	CNGC14 / 816997	AraportID:	AT2G24610	Length:	741	Species:	Arabidopsis thaliana

Alignment Length:	750	Identity:	158/750 - (21%)
Similarity:	279/750 - (37%)	Gaps:	207/750 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 RTTVQISSAIQKKPPL---------------KREDSFLK--RFSTRQI-PET----QETVEDTGS 210
            :.|:::.   :|:.||               |:..:.||  ||...:: ||.    ::.:.|.|
plant    31 KQTIEVG---EKRVPLFKSTTAPFMKQEVLPKKSKTRLKIPRFGRFKVFPENFEIERDKILDPG- 91

  Fly   211 ESASGDVDKSVKRRRRYLQKRRSVVNPDENFYFYWLMMLTVCVLYNLWTLIVRQSFPELQQS--- 272
                ||                :|:..:..|.|:.|:.|.|..|:...:.:.|........:
plant    92 ----GD----------------AVLQWNRVFLFWCLVALYVDPLFFFLSSVKRIGRSSCMTTDLK 136

  Fly   273 ---VPTFWLICDSMTDVVFILDIIVQLRTGYLE-------QGLMVYDDRKLACHYVHSRDFIFDM 327
               |.||:   .::.|:.::|.|:::.||.|:.       :|.:|.|.:.:|..|:.| |||.|:
plant   137 LGIVITFF---RTLADLFYVLHIVIKFRTAYVSRTSRVFGRGELVKDPKLIARRYLRS-DFIVDL 197

  Fly   328 IALIP---------LDLLQLKMGTHPLLRFTRFFKVYRSVRFYYI------------VESRTVWP 371
            ||.:|         |..::.....|..........|....|.|.|            |.:.|.|.
plant   198 IACLPLPQIVSWFILPSIRSSHSDHTTNALVLIVLVQYIPRLYLIFPLSAEIIKATGVVTTTAWA 262

  Fly   372 NLWRVVNLIHILLILAHWFGCFYFLLS----------------------------------EAEG 402
            .  ...||:..:| .:|..|..::|||                                  :...
plant   263 G--AAYNLLQYML-ASHILGSAWYLLSIERQATCWKAECHKESVPLQCVTDFFDCGTLHRDDRNN 324

  Fly   403 FQGDWV----------YPYRPGDYA-TLTR---------KYLGSLYWSTLTLTTIG-DLPTPETN 446
            :|...|          ..:..|.:| .||:         |||..|::....|::.| :|.|..:.
plant   325 WQNTTVVFSNCDPSNNIQFTFGIFADALTKNVVSSPFLEKYLYCLWFGLQNLSSYGQNLSTSTSV 389

  Fly   447 AEYIFTIVSYLIGVFIFATIVGQVGNVITNRNANRLEFERLLDGAKTYMRHHKVPGGMKRRVLRW 511
            .|.:|.|:..:.|:.:||.::|.:...:.:......|:.......:.:|.|..:|..::.||.|:
plant   390 LETMFAILVAIFGLVLFALLIGNMQTYLQSITVRLEEWRLKRRDTEEWMGHRLLPQNLRERVRRF 454

  Fly   512 YDYSWSRGRIQGGGDINTALGLLPDKLKTELALHVNLSVLKKVTIFQECQPEFLHDLVLKMKAYI 576
            ..|.|...|   |.|..|.|..||..|:.::..|:.|.::::|.:|.:...:.|..:..::.:.:
plant   455 VQYKWLATR---GVDEETILHSLPADLRRDIQRHLCLDLVRRVPLFAQMDDQLLDAICERLASSL 516

  Fly   577 FTPGDSICRKGEVAREMFIIADGILEVLSETGKVL-----TTMKAGDFFGE----IGILNLDGLN 632
            .|.|:.|.|:|:...||..|..|.||..:..|...     .|::.|||.||    ..:|....:|
plant   517 STQGNYIVREGDPVTEMLFIIRGKLESSTTNGGRTGFFNSITLRPGDFCGEELLAWALLPKSTVN 581

  Fly   633 --KRTADVRSVGYSELFSLSREDVLAAMKDYPDAQEILQTLGRKRLMEV---------------- 679
              ..|..||::...|.|:|...|:......:       :.|..|:|...
plant   582 LPSSTRTVRALEEVEAFALQAGDLKFVANQF-------RRLHSKKLQHTFRYYSHQWRTWAACFV 639

  Fly   680 -----RCVNKKYAKAQS---------DKEAAAYAA----AHPHHHQSHHQGQVHQSDSSENSASK 726
                 |...||.||:.|         ::||.|.||    :|....||..:.:.|.|:...:.|:.
plant   640 QVAWRRYKRKKLAKSLSLAESFSSYDEEEAVAVAATEEMSHEGEAQSGAKARHHTSNVKPHFAAT 704

  Fly   727 KIVDKLKHDVKGFRNVLKKSRTSRK-SDESLEMQP 760
            .:..:...:.:         ||:.| .|..:.|.|
plant   705 ILASRFAKNTR---------RTAHKLKDVEIPMLP 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cngl	NP_001245691.1	Ion_trans	260..481	CDD:278921	61/309 (20%)
		Ion_trans_2	382..476	CDD:285168	27/148 (18%)
		Crp	550..>680	CDD:223736	33/161 (20%)
		CAP_ED	556..668	CDD:237999	29/122 (24%)
CNGC14	NP_001324934.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920