Protein Alignment Cngl and kcnh6b

DIOPT Version :9

• Sequence 1: NP_001245691.1
• Gene: Cngl / 32468
• FlyBaseID: FBgn0263257
• Length: 1970
• Species: Drosophila melanogaster
• Sequence 2: XP_021328182.1
• Gene: kcnh6b / 570070
• ZFINID: ZDB-GENE-121214-55
• Length: 893
• Species: Danio rerio
• Alignment Length: 972
• Identity: 205/972 - (21%)
• Similarity: 379/972 - (38%)
• Gaps: 242/972 - (24%)

  Fly   162 QRWMKLRTTVQIS--SAIQKKPPLKREDSFLKRFSTRQIPETQETVEDTGSESASGDVDKSVKRR 224
            ||:..|:::::.|  |:.::...|.|..||  |.:.|:...:..:...:..|.    |...||.|
Zfish     2 QRFNGLKSSLRNSRTSSSERMKALNRFHSF--RLNLRRPRRSNPSTAHSNIEL----VTPKVKER 60

  Fly   225 RRYLQKRRSVV--------------NPDEN---------FYFYWLMMLTVCVLYN-LWT-----L 260
            .:.:.::.:.|              .||.:         |...|..::.:.|||. ::|     .
Zfish    61 TQNVTEKVTQVLSLGADVLPEYKLQAPDVHKWIMLHYSPFKAIWDWVILLLVLYTAVFTPFSAAF 125

  Fly   261 IVRQSFPELQQSVPTFWLIC------DSMTDVVFILDIIVQLRTGYLEQG-LMVYDDRKLACHYV 318
            ::.:...|.:|   |....|      |.:.||:||.||::..||.|:... .:|...:::|.||:
Zfish   126 LLNELEDERRQ---TCGYTCNPLNVVDVIVDVLFIADIVITFRTTYVNHNDEVVTHPKRIAIHYI 187

  Fly   319 HSRDFIFDMIALIPLDLLQLKMGTHP-------LLRFTRFFKVYRSVRFYYIVESRTVWPNLWRV 376
            ....|| ||:|.||.|||..:.|:..       ||:..|..::.|..|            .|.|.
Zfish   188 KGWFFI-DMVAAIPFDLLIFRSGSDETTATLIGLLKTARLLRLVRVAR------------KLDRY 239

  Fly   377 ----VNLIHILL----ILAHWFGCFYFLLSEAEG--FQGDWV--------YPYRPGDYA---TLT 420
                ..::.:|:    ::|||..|.::.:...|.  .:..|:        ..|...|.:   ::.
Zfish   240 SEYGAAVLFLLMCTFGLIAHWLACIWYAIGHVERPYMKTGWLDNLADQLGKRYNDSDASSGPSIQ 304

  Fly   421 RKYLGSLYWSTLTLTTIG-DLPTPETNAEYIFTIVSYLIGVFIFATIVGQVGNVITNRNANRLEF 484
            .||:.:||::..:||::| ...:|.||:|.:|:|....||..::|:|.|.|..:|....:....:
Zfish   305 DKYITALYFTFSSLTSVGFGNVSPNTNSEKMFSICVMFIGSLMYASIFGNVSAIIQRLYSGTTRY 369

  Fly   485 ERLLDGAKTYMRHHKVPGGMKRRVLRWYDYSWSRGRIQGGGDINTALGLLPDKLKTELALHVNLS 549
            ...:...|.::|.|::|||:::|:..::.::||   ...|.|:|..|...|:.|:.::.||:|.|
Zfish   370 HTQMLRVKEFIRFHQIPGGLRQRLEEYFQHAWS---YTNGIDMNAVLKGFPECLQADICLHLNRS 431

  Fly   550 VLKKVTIFQECQPEFLHDLVLKMKAYIFTPGDSICRKGEVAREMFIIADGILEVLSETGKVLTTM 614
            :|:...:|:......|..|.::.::....|||::..:|::.|.:..|:.|.::| |:...||..:
Zfish   432 LLQNCKVFRGASKACLRALAVRFRSTHSPPGDALYHQGDMLRALHFISRGSIQV-SQHNIVLAIL 495

  Fly   615 KAGDFFGE-IGILNLDGLNKRTADVRSVGYSELFSLSREDVLAAMKDYP---------------- 662
            ...|.||| :.:....|  ...|||.::.|.:|..:.|:|:|..:..||
Zfish   496 GKNDVFGEPVNLYAEPG--HSNADVTALTYCDLHRIRRDDLLEVLDMYPAFGESFWRNLEITFNL 558

  Fly   663 -DAQEIL---------QTLGRKRLMEVRCVNKKYAKAQSDKE--AAAYAAAHPHHHQSHHQGQVH 715
             |.::::         |...|:.|::.|  |:.....|:|..  .:|....|.|||..||....|
Zfish   559 RDVEQMMPSESLECSYQARHRQNLLDRR--NRPDGMDQNDSSRLCSALGLHHHHHHHHHHPAAAH 621

  Fly   716 Q----------SDSSEN-----------------------------SASKKI---VDKLKHDVKG 738
            .          ..||||                             ..|::|   :..:.....|
Zfish   622 MHWEDLCSYSTQQSSENLSHCELCTSDTEHLDYPSPAGRLIPPSASGVSREIGVEMGYMARPPSG 686

  Fly   739 FRNVLKKSRTSRKSDESLEMQPLHNTSPRGSKILLKRMSRVRSDEKDADSAEAKDELHD------ 797
            ..:......|...||:.|....:..:.|          .::.:|.:..:.....|.||.
Zfish   687 LYHYWPDPHTPHFSDQPLRPPSIQTSFP----------PQIFADHQPGEVEARLDLLHSQLNRLE 741

  Fly   798 -KTPSPIGAGLPLLQRLRLLKEKQDREERAVKSTPPQKSPPHSHVTCTLSPQESIQEEPEREFSE 861
             :..:.|...|.||||      :......|..:..|.:.||                :|...:..
Zfish   742 TRMTTDINVILQLLQR------QMAPVPPAYSTVLPDRHPP----------------DPTALYRN 784

  Fly   862 GFPLIQRLQQLKIKNEPQANAAEPGVVM-VNTPPNISSKIDSHFAASQAGASHPGPNGGA----- 920
            ..|::..|..:            |.:.: .||....|::.:|.|.|:..|:...|.:.||
Zfish   785 NTPVLHSLYPI------------PNIQLDTNTAIQSSAQPESMFKANSQGSLSSGVHMGAASDDC 837

  Fly   921 ----IGISAPGQSLTVAQIKPIMKVSFKQKIQQMQGGGGGASSSPGPSTGAIAKKEPPKSLA 978
                ..:|.|.....:.. .|::.||.:            ..|.||....:...::|.|.::
Zfish   838 VPETTSVSTPALQPALMD-APMLCVSLR------------FPSLPGKLDTSSHSEDPQKHMS 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cngl	NP_001245691.1	Ion_trans	260..481	CDD:278921	65/256 (25%)
		Ion_trans_2	382..476	CDD:285168	29/111 (26%)
		Crp	550..>680	CDD:223736	34/156 (22%)
		CAP_ED	556..668	CDD:237999	30/129 (23%)
kcnh6b	XP_021328182.1	Ion_trans	103..364	CDD:306908	70/276 (25%)
		CAP_ED	438..549	CDD:237999	29/113 (26%)
		PAT1	<681..>831	CDD:330585	32/193 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910