Protein Alignment Cngl and Cngb3

DIOPT Version :9

• Sequence 1: NP_001245691.1
• Gene: Cngl / 32468
• FlyBaseID: FBgn0263257
• Length: 1970
• Species: Drosophila melanogaster
• Sequence 2: NP_038955.1
• Gene: Cngb3 / 30952
• MGIID: 1353562
• Length: 694
• Species: Mus musculus
• Alignment Length: 594
• Identity: 172/594 - (28%)
• Similarity: 297/594 - (50%)
• Gaps: 77/594 - (12%)

  Fly   131 AHSSDSKSPSQRKSRIGDGASDPD----SDWTRS----------NQRWMKLRTTVQISSAIQK-- 179
            :||.:..|..:...|  |...:||    ::.||:          .:|.:..:|.|..:|.|.:
Mouse    58 SHSKEDNSTGENSLR--DFTPNPDPECRAELTRTMAEMEKTRTGKERPVSFKTKVLETSIINEYT 120

  Fly   180 ------------------KPPLKREDSFLKRFSTRQIPETQETVEDTGSESASGDVDKS------ 220
                              |..|..|::|         ||.:.:.:...|.:.|...:.:
Mouse   121 DAHLHNLVERMRERTALYKKTLTEEENF---------PEVEASSQTAMSTNISPKQENNSKLKEH 176

  Fly   221 ------------VKRRRRYLQKRRSVVNPDENFYFYWLMMLTVCVLYNLWTLIVRQSFPELQQSV 273
                        ||...|.:...||:.:..:..|..||:::|:...:|.|.|.||..||......
Mouse   177 QDTFSFKPQRVPVKEHLRRMILPRSIDSYTDRVYLLWLLLVTIAYNWNCWLLPVRLVFPCQTPDN 241

  Fly   274 PTFWLICDSMTDVVFILDI-IVQLRTGYLEQGLMVYDDRKLACHYVHSRDFIFDMIALIPLDLLQ 337
            ..:|:|.|.:.|::::.|| ::|.|..::..|.::.|..:|..:|..|..|..|:.:|:|.::|.
Mouse   242 KNYWIITDIVCDIIYLCDILLIQPRLQFVRGGEIIVDSNELKRNYRSSTKFRMDVASLLPFEVLY 306

  Fly   338 LKMGTHPLLRFTRFFKVYRSVRFYYIVESRTVWPNLWRVVNLIHILLILAHWFGCFYFLLSEAEG 402
            :..|.:|:.|..|..|......|.:.:||......::||:.....||.|.|...|.|:..|:.||
Mouse   307 IFFGVNPIFRANRILKYTSFFEFNHHLESIMDKAYVYRVIRTTGYLLFLLHINACVYYWASDYEG 371

  Fly   403 F-QGDWVYPYRPGDYATLTRKYLGSLYWSTLTLTTIGDLPTPETNAEYIFTIVSYLIGVFIFATI 466
            . ...|||   .|:    ..|||...||:..||.|||.||.|:|:.|.:|..:::..|||:|:::
Mouse   372 IGSTKWVY---NGE----GNKYLRCFYWAVRTLITIGGLPEPQTSFEIVFQFLNFFSGVFVFSSL 429

  Fly   467 VGQVGNVITNRNANRLEFERLLDGAKTYMRHHKVPGGMKRRVLRWYDYSWSRGRIQGGGDINTAL 531
            :||:.:||....||:..|:..:|....||..:.:|..::.||..|.:|:|:..||.   |.:..|
Mouse   430 IGQMRDVIGAATANQNYFQACMDHIIAYMNKYSIPQSVQYRVRTWLEYTWNSQRIL---DESNLL 491

  Fly   532 GLLPDKLKTELALHVNLSVLKKVTIFQECQPEFLHDLVLKMKAYIFTPGDSICRKGEVAREMFII 596
            ..||..::..:||.:|.|::.||.:|:.|..:.::||:|::|:.|:.|||.:|:|||:.:||:||
Mouse   492 ENLPTAMQLSIALDINFSIIDKVELFKGCDTQMIYDLLLRLKSTIYLPGDFVCKKGEIGKEMYII 556

  Fly   597 ADGILEVLS--ETGKVLTTMKAGDFFGEIGILNLDGLNKRTADVRSVGYSELFSLSREDVLAAMK 659
            ..|.::||.  :..:||.|:|||..||||.:|...|.|:|||||.:.|::.|.:|.::.:...:.
Mouse   557 KHGEVQVLGGPDGAQVLVTLKAGSVFGEISLLAKGGGNRRTADVVAHGFANLLTLDKKTLQEILL 621

  Fly   660 DYPDAQEIL 668
            .||.::::|
Mouse   622 HYPTSKKLL 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cngl	NP_001245691.1	Ion_trans	260..481	CDD:278921	71/222 (32%)
		Ion_trans_2	382..476	CDD:285168	37/94 (39%)
		Crp	550..>680	CDD:223736	47/121 (39%)
		CAP_ED	556..668	CDD:237999	44/113 (39%)
Cngb3	NP_038955.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..82		7/25 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..177		5/39 (13%)
		Ion_trans	228..445	CDD:278921	72/223 (32%)
		Crp	510..>640	CDD:223736	47/121 (39%)
		CAP_ED	516..624	CDD:237999	42/107 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835129
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	1	1.000	-	-		FOG0000167
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850