DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9164 and XYLT1

DIOPT Version :9

Sequence 1:	NP_573021.1	Gene:	CG9164 / 32467	FlyBaseID:	FBgn0030634	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_071449.1	Gene:	XYLT1 / 64131	HGNCID:	15516	Length:	959	Species:	Homo sapiens

Alignment Length:	194	Identity:	40/194 - (20%)
Similarity:	58/194 - (29%)	Gaps:	68/194 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 IERFAEFPSFHSPRFPMPSR------KMTIRW---------CRDLKYINRDLPIYADYKSDFYTA 89
            ||..||| :.:.|...:|.|      |:...|         ...|.:.||. ||..:.....:..
Human   799 IESTAEF-THYKPPLNLPLRPGVWTVKILHHWVPVAETKFLVAPLTFSNRQ-PIKPEEALKLHNG 861

  Fly    90 LPSDVSAALQSLPALTALASFP-------------GSGNTWLRYLLQQATGILTGSIYKDYGLLK 141
             |...:...||..:|..:.|.|             .|..|.|...|..    |.|.::....:..
Human   862 -PLRNAYMEQSFQSLNPVLSLPINPAQVEQARRNAASTGTALEGWLDS----LVGGMWTAMDICA 921

  Fly   142 TG---FPAENVCNSSVLLVKTHEWGSKAWAPFSKAILLVRDPEKAIIAEFNRQSGGHIGFASPD 202
            ||   .|....|:.:            ||:.||.      ||:            ..:|...||
Human   922 TGPTACPVMQTCSQT------------AWSSFSP------DPK------------SELGAVKPD 955

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9164	NP_573021.1	Sulfotransfer_1	107..>271	CDD:304426	21/112 (19%)
XYLT1	NP_071449.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..259
		Branch	328..580	CDD:280621
		UDP-xylose binding. /evidence=ECO:0000269\|PubMed:29681470, ECO:0007744\|PDB:6EJ7	390..392
		UDP-xylose binding. /evidence=ECO:0000269\|PubMed:29681470, ECO:0007744\|PDB:6EJ7	494..495
		UDP-xylose binding. /evidence=ECO:0000269\|PubMed:29681470, ECO:0007744\|PDB:6EJ7	598..599
		Xylo_C	613..793	CDD:289306
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	940..959		7/34 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156643
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930