DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9164 and Wscd2

DIOPT Version :9

Sequence 1:	NP_573021.1	Gene:	CG9164 / 32467	FlyBaseID:	FBgn0030634	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_796266.2	Gene:	Wscd2 / 320916	MGIID:	2445030	Length:	571	Species:	Mus musculus

Alignment Length:	291	Identity:	102/291 - (35%)
Similarity:	144/291 - (49%)	Gaps:	40/291 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 EFP-----------SFHSPRFPMPSR---KMTIRWCRDLKYINRDLPIYADYKSDFYTALPSDVS 95
            |||           .|.:.|||:..|   ::..:.|...::.:...|   .|...:.|.:..:..
Mouse   275 EFPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTP---SYFIVYQTQVQDNRC 336

  Fly    96 AALQSLPA----LTALASFPGSGNTWLRYLLQQATGILTGSIYKDYGLLKTGFPAE--------N 148
            ...:.|||    |.|||||||:||||.|:|::.|||..|||.|.|..|...||..|        .
Mouse   337 MDRRFLPAKSKKLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRT 401

  Fly   149 VCNSSVLLVKTHEWGSKAWAPFSKAILLVRDPEKAIIAEFNRQSGGHIGFASPDRYKRTKGKYWQ 213
            :|      :||||.|.|....|..||||:|:|.||::|||||:.|||||||:   :...|||.|.
Mouse   402 IC------IKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAA---HAHWKGKEWP 457

  Fly   214 QFVSNKLKGWEMMNLSWARNFTGSIKVVFYDDLVHHTERELRSILDFLQFPINEQLMRCAIMRKE 278
            :||.|....|....|.|.: |..::.||.::||......:|..::..|...:.|..:.|...:|:
Mouse   458 EFVRNYAPWWATHTLDWLK-FGKTVLVVHFEDLKQDLFTQLGRMVSLLGVAVREDRLLCVESQKD 521

  Fly   279 GIFRRK-KRLLSFDPYTESMRAEVQNRRRIV 308
            |.|:|. .|.|.:||||..||..:....|:|
Mouse   522 GNFKRSGLRKLEYDPYTAEMRRTIAAYIRMV 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9164	NP_573021.1	Sulfotransfer_1	107..>271	CDD:304426	70/171 (41%)
Wscd2	NP_796266.2	WSC	134..225	CDD:214616
		WSC	236..330	CDD:214616	11/57 (19%)
		Sulfotransfer_3	<421..>513	CDD:389806	37/95 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847048
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4157
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002523
OrthoInspector	1	1.000	-	-		otm43076
orthoMCL	1	0.900	-	-		OOG6_107265
Panther	1	1.100	-	-	O	PTHR45964
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2335
SonicParanoid	1	1.000	-	-		X1657
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730