Protein Alignment Prp5 and rhlE

DIOPT Version :10

• Sequence 1: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Sequence 2: NP_415318.1
• Gene: rhlE / 945425
• ECOCYCID: EG11235
• Length: 454
• Species: Escherichia coli
• Alignment Length: 443
• Identity: 161/443 - (36%)
• Similarity: 251/443 - (56%)
• Gaps: 30/443 - (6%)

  Fly   516 GVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILD-QPSME 579
            |:|...:..:...|:.:|||||.|||||::.||||:..|:||:|||..|.||:.:|::. ||..:
E. coli     7 GLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMASAQTGTGKTAGFTLPLLQHLITRQPHAK 71

  Fly   580 DGDGAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRM 644
            ......|:|:.|||||..|||:::|.:||.|.:|.:.|:||..|:.|:.:|:.|.:::|.||||:
E. coli    72 GRRPVRALILTPTRELAAQIGENVRDYSKYLNIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRL 136

  Fly   645 IDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVRPDRQTVMFSATFPRQMEALA 709
            :|:...|:   ..|.:|..:||||||||.||||...:.|::..:...||.::|||||...::|||
E. coli   137 LDLEHQNA---VKLDQVEILVLDEADRMLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALA 198

  Fly   710 RRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELL--GIYQEAGSIIVFVDKQENADI 772
            .::|..|:|:.|..|:....:|.|||..::...|...|..::  |.:|:   ::||...:..|:.
E. coli   199 EKLLHNPLEIEVARRNTASDQVTQHVHFVDKKRKRELLSHMIGKGNWQQ---VLVFTRTKHGANH 260

  Fly   773 LLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNH 837
            |...|.|......::||...|..|...:.|||||.:|:|:||.:||||||:::|..||||::||.
E. coli   261 LAEQLNKDGIRSAAIHGNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNV 325

  Fly   838 YEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAM--DLSGTLIPAELQALWTEY------ 894
            .||||||.||||||...|.|.:.:..::.:...||.:.:  ::....||.        |
E. coli   326 PEDYVHRIGRTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPG--------YEPDPSI 382

  Fly   895 KALQEAEGKTVHTGGG---FSGKGFKFDEQEFNAAK--ESKKLQKAALGLADS 942
            ||.....|:....|||   ..|:|.:...:....||  .:|..:|.:..|.|:
E. coli   383 KAEPIQNGRQQRGGGGRGQGGGRGQQQPRRGEGGAKSASAKPAEKPSRRLGDA 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653
		DEAD-like_helicase_N	454..899	CDD:475120	149/393 (38%)
		KH-I_DDX46	1121..1223	CDD:411901
rhlE	NP_415318.1	PRK10590	1..454	CDD:236722	161/443 (36%)