Protein Alignment Prp5 and SoYb

DIOPT Version :10

• Sequence 1: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Sequence 2: NP_609335.3
• Gene: SoYb / 34331
• FlyBaseID: FBgn0051755
• Length: 1476
• Species: Drosophila melanogaster
• Alignment Length: 899
• Identity: 155/899 - (17%)
• Similarity: 317/899 - (35%)
• Gaps: 239/899 - (26%)

  Fly   169 LSTSCSEEEVEEIDKEEQ------QR----RLEQEMIKRRERIE------------------RW- 204
            |...||.|..:::..|::      ||    :|.:.:::||:..|                  .|
  Fly    46 LKDYCSSERTKQVYVEDERVIVRYQRWSPPKLVRGVVRRRQNEEYLVWILDYGFNLCCSVWDLWP 110

  Fly   205 ---RAERK----RDTKAAVVAPSLVNSAKKWS----------LEDESE----------------- 235
               ...|.    ::...|::||   :|...||          |||.::
  Fly   111 LPDHLSRSLCDFKEGGVALIAP---HSGSVWSRSAIESLDKQLEDANQLTFQVVHRGKSNRNFGL 172

  Fly   236 ---------EDDSNPAPPLDSGK-KDAEPDSPPSKFHSIRK-RFDDDVVESKFSPVKRPTFSKSF 289
                     ||.:|.....|.|: |:....:.|.:..|..| ..:|..:::      ||...:..
  Fly   173 LKFRSSCQTEDAANFLIKQDQGRCKETLTMAIPYEDISFEKAEINDMAIDT------RPRLRRIL 231

  Fly   290 GKLGIGLATKAEADIKKEPPPVDTKKEIKKK------------PEPV--AAKMEIVEE---PTVA 337
             :|.:.|:..|     ||..|..:..:.||.            |..|  .:|::.:.|   .|..
  Fly   232 -ELVVLLSENA-----KESTPTPSAIQQKKLDALLQSHETYLIPNSVKLLSKVQSISESSMQTAL 290

  Fly   338 AGEKTKKEPEQPHVGAKSEPEVEDKPQPEA---EPEDEID-----PLDAYMQE------------ 382
            |....:...|.||...:|    ||..:.|.   |.|:..:     .|.:|.|:
  Fly   291 ANRSKQISKELPHKANQS----EDNRKKEVKYLESENLSECLSKVKLSSYQQKNTDSSTLSGPRN 351

  Fly   383 -------VNNEMRRVNNFVNPPAKSQGVVILTGVAKKKT---TTLKKGEVIEQNMDSLEYSSEDE 437
                   .|:.:|:.....    ||.|..:.|.::...|   |.......:..:||.:|....|.
  Fly   352 LASSSTNSNSNVRKSMTLF----KSSGAHLTTSLSVPLTENCTNQSNNRTVVFSMDKMEQIFNDM 412

  Fly   438 LEDIRDTAVNLAMKHRKELAKIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKY---RSDLEGIQ 499
            |.  ::.:.....|:|.::...:.|:                    |...|||.   ||:..|.:
  Fly   413 LG--KNPSERSVQKNRSQMPNSNVST--------------------TKRCVEKMHVCRSENMGDR 455

  Fly   500 VKGKGCPK------------PIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSGRDLIG 552
             |...|.|            |:.::.:..:....:..:..|.|:.|.|.|..|.|.:::...|:.
  Fly   456 -KPSVCLKHLVLAHSPEPVNPVTSYKELPLGNTILNAMDDLNFQTPLPTQIYAWPHLVNRGSLVL 519

  Fly   553 IAKTGSGKTLAF-------ILPMFRHILDQPSMEDGDGAIAIIMAPTRELCMQIGKDIRKFSKSL 610
            :..:|:|::.::       :|..|.::..........|.:||::..:.|...::........|..
  Fly   520 VNPSGTGRSWSYLPVICSSVLSSFENVTSNLDTRIAPGPLAILIVDSVENAKKLASHCEFLMKDF 584

  Fly   611 GLRPVCVYG--GTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEAD--R 671
            ..:.:.|..  ...:.:....|.....::|.|...:.::| :|...:.|..|:.:::.|:.|  |
  Fly   585 NTQNLKVVNTHAHSMMDVYMMLLNSCGVLVTTLAHLNNIL-SNELPLVNPTRLEFIIFDDYDRKR 648

  Fly   672 MFDMGFEPQVMRIIDNVRP-DRQTVMFSATF-PRQMEALARRILKKPI-------EVIVGGRSVV 727
            :.:.....:|.:.::::.. .:|.|:.:..: ..:.:.|..|..|..|       ..:.||
  Fly   649 LDNAELLKEVFQKVNSIGGLSKQLVLVAQQWHSERFQKLLNRTTKPLILFGDFLEAALYGG---- 709

  Fly   728 CKEVEQHVVILNDDAKFFKLLELLGIYQEAGS---IIVFVDKQENADILLRDLMKASYPCMSLHG 789
               ::.:|.:.:...|..:||::|.  ::.||   .:::...|...:.|...|::|...|:.:..
  Fly   710 ---LKFNVTLRSSALKARQLLDILA--EQDGSKKRTLIYCKNQMELEELSAILIEAGLQCVDISK 769

  Fly   790 GIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAGKK 854
            ..:|           |....:|:..|...:.|.|:::.|::::.:|..:..:..|
  Fly   770 AQNQ-----------SPNRLMLVDDSQVRKQLPVRNIQLLIHFSLPESWLRFSRR---------- 813

  Fly   855 GSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQAL-WTEYKALQEAEGKTVHT 907
              .:|.....::.:...|.|..||...::..|..|. |.......:..|.|..:
  Fly   814 --FHTMADNIRNLFTKPIGRGQDLITYILMDENNAKEWPRIMKFLQDHGLTTQS 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653	26/135 (19%)
		DEAD-like_helicase_N	454..899	CDD:475120	78/483 (16%)
		KH-I_DDX46	1121..1223	CDD:411901
SoYb	NP_609335.3	TUDOR	15..115	CDD:425754	12/68 (18%)
		DEAD-like_helicase_N	488..>646	CDD:475120	26/158 (16%)
		TUDOR	930..1043	CDD:425754