Protein Alignment Prp5 and Ddx3y

DIOPT Version :10

• Sequence 1: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Sequence 2: NP_036138.1
• Gene: Ddx3y / 26900
• MGIID: 1349406
• Length: 658
• Species: Mus musculus
• Alignment Length: 472
• Identity: 172/472 - (36%)
• Similarity: 260/472 - (55%)
• Gaps: 35/472 - (7%)

  Fly   484 TAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSGR 548
            |..:.||| .|:. ::..|..||..|:.::...:.:..|..:....:.:|||:|..|||.|...|
Mouse   155 TGINFEKY-DDIP-VEATGNNCPPHIENFSDIEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKR 217

  Fly   549 DLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDG------------------AIAIIMAPTREL 595
            ||:..|:||||||.||:||:...|     ..||.|                  .|::::||||||
Mouse   218 DLMACAQTGSGKTAAFLLPILSQI-----YTDGPGEALKAMKENGRYGRRKQYPISLVLAPTREL 277

  Fly   596 CMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRR 660
            .:||.::.||||....:||..||||....:||.:|:||..::|.||||::||:  ..|:: .|..
Mouse   278 AVQIYEEARKFSYRSRVRPCVVYGGADTVQQIRDLERGCHLLVATPGRLVDMM--ERGKI-GLDF 339

  Fly   661 VTYVVLDEADRMFDMGFEPQVMRII--DNVRPD--RQTVMFSATFPRQMEALARRILKKPIEVIV 721
            ..|:||||||||.|||||||:.||:  |.:.|.  |.|:|||||||::::.|||..|.:.|.:.|
Mouse   340 CKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 404

  Fly   722 GGRSVVCKEVEQHVVILNDDAKFFKLLELLGIYQEAGSIIVFVDKQENADILLRDLMKASYPCMS 786
            |......:.:.|.||.:.:..|...||:||....:....:|||:.::.||.|...|.:..|.|.|
Mouse   405 GRVGSTSENITQKVVWVEELDKRSFLLDLLNATGKDSLTLVFVETKKGADSLENFLFQERYACTS 469

  Fly   787 LHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRA 851
            :||...|.||:..:..|:||:..:|:||:|||||||:.::..|:|:|:|:..|:||||.|||||.
Mouse   470 IHGDRSQKDREEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRV 534

  Fly   852 GKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQALWTE--YKALQEAEGKTVHTGGGFSGK 914
            |..|.|.:|..........|::..:..:...:|:.|:::..|  ||.......|: ...|||..:
Mouse   535 GNLGLATSFFNERNLNITKDLLDLLVEAKQEVPSWLESMAYEHHYKGSSRGRSKS-RFSGGFGAR 598

  Fly   915 GFKFDEQEFNAAKESKK 931
            .::......||...|.:
Mouse   599 DYRQSSGSANAGFNSNR 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653
		DEAD-like_helicase_N	454..899	CDD:475120	165/438 (38%)
		KH-I_DDX46	1121..1223	CDD:411901
Ddx3y	NP_036138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..143
		DEADc_DDX3	159..409	CDD:350809	104/259 (40%)
		Q motif	179..207		4/27 (15%)
		DEAD box	346..349		2/2 (100%)
		SF2_C_DEAD	414..544	CDD:350174	53/129 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..627		3/19 (16%)