Protein Alignment Prp5 and glh-4

DIOPT Version :10

• Sequence 1: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Sequence 2: NP_491207.3
• Gene: glh-4 / 171941
• WormBaseID: WBGene00001601
• Length: 1156
• Species: Caenorhabditis elegans
• Alignment Length: 490
• Identity: 143/490 - (29%)
• Similarity: 238/490 - (48%)
• Gaps: 76/490 - (15%)

  Fly   458 KIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEM 522
            |||......|...|   ||:|::            :..:|.::    .|:.:.
 Worm   715 KIDFDQKVVASTGK---VEIPDM------------ASFDGFKI----LPQDLH------------ 748

  Fly   523 EVLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHIL-----DQPSMEDGD 582
            :.|:|:...:|||||..:...||.|.|::..|.|||||||||::|....::     |:...::..
 Worm   749 DNLKRMKMNRPTPIQRASFFPIMHGNDVVACAHTGSGKTLAFLIPFVIKLMEEFEKDRDVTDEKP 813

  Fly   583 GAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAE--IIVCTPGRMI 645
            ....:|:||||||..|.....|:.:...||:....:||...:..:..|:..::  |:|.|.||:.
 Worm   814 SPRLLIVAPTRELVNQTFTTARQLTYETGLKCGLAFGGYSRNANVQHLRSFSQLNILVATMGRLQ 878

  Fly   646 DMLAANSGRVTNLRRVTYVVLDEADRMFDMG-FEPQVMRIIDNV-RPDRQTVMFSATFPRQMEA- 707
            |.:  |:|.| :|.::.|:||||||||.|.. |..:|.:||.:. ...:|||:|||:|...:::
 Worm   879 DFV--NAGEV-SLSKMKYIVLDEADRMVDSNDFGEEVSKIIGSPGERTQQTVLFSASFSEDLQSD 940

  Fly   708 -LARRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLGIYQ-----------EAGSI 760
             |.:.:.:....:.|.......::::|.::.:....|...:.:||||.:           |....
 Worm   941 DLPKFVKEGYTMLQVDKFGTANEKIDQKILPVPRTEKRDAIYKLLGIDENTVTLLPDAPIEKQKT 1005

  Fly   761 IVFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKD 825
            ::||:..:..|.|...:..|....:|:|...:|..||.|:.||:.||.:.::|::|.||||::..
 Worm  1006 LIFVNSVKFCDTLAALISSAGVSTISMHSYQNQEQRDRTLDDFRRGKYQCMVASNVCARGLNIAG 1070

  Fly   826 LILVVNYDVP--NHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQ 888
            |..|||||:|  |.:::||:|.|||||||..|::..|:..|...   |||..  |...|..|:.:
 Worm  1071 LDHVVNYDMPDKNGFDEYVNRIGRTGRAGFTGTSTAFVDVENDT---DIIPC--LVSILNEAKKE 1130

  Fly   889 A-LWTEYKALQEAEGKTVHTGGGFSGKGFKFDEQE 922
            . .|....|..:.||            |..::|||
 Worm  1131 VPEWLTEGAGHQEEG------------GDDWNEQE 1153

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653
		DEAD-like_helicase_N	454..899	CDD:475120	137/465 (29%)
		KH-I_DDX46	1121..1223	CDD:411901
glh-4	NP_491207.3	dermokine	<388..>590	CDD:455732
		PTZ00368	572..685	CDD:173561
		SrmB	734..1109	CDD:440279	120/405 (30%)