Protein Alignment Prp5 and vbh-1

DIOPT Version :10

• Sequence 1: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Sequence 2: NP_001021793.1
• Gene: vbh-1 / 171888
• WormBaseID: WBGene00006888
• Length: 660
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 184/601 - (30%)
• Similarity: 284/601 - (47%)
• Gaps: 103/601 - (17%)

  Fly   349 PHVGAKSEPEVEDKPQPE-------AEPEDEIDPLDAYMQEVNNEMRRVNNFVNPPAKSQGVVIL 406
            ||.|....|..:.:||.:       :|..:..|  :......||.....|.|.|..|:|.
 Worm    38 PHAGFVPSPYFQGQPQQQQHFKMGYSENFENFD--ENGSSGYNNFADSGNGFNNNGAESN----- 95

  Fly   407 TGVAKKKTTTLKKGEVIEQNMDSLEYSSEDELEDIRDTAVNLAMKHRKELAKIDHSSVTYAPFRK 471
                             :......|| ||..|....|:.:|                     |.|
 Worm    96 -----------------QWGGAPAEY-SESNLFHRTDSGIN---------------------FDK 121

  Fly   472 NFYVEVPELTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPI 536
              |..:|                   ::|.|...|..|:.:.:.|.....||.:.|.|:.||||:
 Worm   122 --YENIP-------------------VEVSGDSVPAAIEHFNEAGFGPAVMENVNRSGYSKPTPV 165

  Fly   537 QCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHIL-------DQPSMEDGDGA---IAIIMAP 591
            |..:||.:::.|||:..|:||||||.||:||:.:|||       ..|:..:|...   .|::::|
 Worm   166 QKHSIPTLLANRDLMSCAQTGSGKTAAFLLPIIQHILAGGPDMVKPPAFTNGRRTYYPCALVLSP 230

  Fly   592 TRELCMQIGKDIRKFSKSLGLRPVCVYGG-TGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRV 655
            ||||.:||.|:..|||....::...:||| ....:|:..|:.|..|::.||||:||::  ..|.:
 Worm   231 TRELAIQIHKEATKFSYKSNIQTAILYGGRENYRDQVNRLRAGTHILIATPGRLIDII--EQGFI 293

  Fly   656 TNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVRPD---RQTVMFSATFPRQMEALARRILK-KP 716
             .|....|:||||||||.|||||||:.:|:....|.   |.|.|||||||::::.||:..|| ..
 Worm   294 -GLAGCRYLVLDEADRMLDMGFEPQIRKIVGQGMPPKTARTTAMFSATFPKEIQVLAKDFLKDNY 357

  Fly   717 IEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLGIYQEAGSIIVFVDKQENADILLRDLMKAS 781
            |.:.||......:.:||.::.:|:..|...|:|:|........::|||:.:..|:.|...|.:..
 Worm   358 IFLAVGRVGSTSENIEQRLLWVNEMEKRSNLMEILMNEHSENLVLVFVETKRGANELAYFLNRQQ 422

  Fly   782 YPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCG 846
            ...:|:||.:.|.:|:..:..|:||:..:|:||:|||||||:.::..|:|||:|...::||||.|
 Worm   423 IRSVSIHGDLKQIERERNLELFRSGQCPILVATAVAARGLDIPNVRHVINYDLPGDSDEYVHRIG 487

  Fly   847 RTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQALWTEYKALQEAEGKTVHTGGGF 911
            ||||.|..|.|.:|...:......|:...:..|...:|.     |....|   |||:   .|||.
 Worm   488 RTGRCGNLGIATSFFNDKNRGIGRDLKNLIVESNQEVPE-----WLHQVA---AEGR---IGGGQ 541

  Fly   912 SGKGFKFDEQEFNAAK 927
            .|...:|...::...:
 Worm   542 RGGNRRFGATDYRVGR 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653	8/40 (20%)
		DEAD-like_helicase_N	454..899	CDD:475120	154/459 (34%)
		KH-I_DDX46	1121..1223	CDD:411901
vbh-1	NP_001021793.1	SrmB	141..526	CDD:440279	143/387 (37%)