Protein Alignment HDAC6 and HDA08

DIOPT Version :10

• Sequence 1: NP_001259569.1
• Gene: HDAC6 / 32461
• FlyBaseID: FBgn0026428
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_563817.1
• Gene: HDA08 / 837366
• AraportID: AT1G08460
• Length: 377
• Species: Arabidopsis thaliana
• Alignment Length: 345
• Identity: 105/345 - (30%)
• Similarity: 163/345 - (47%)
• Gaps: 28/345 - (8%)

  Fly   123 KEHYECPERFTRVLERCRELNLTERCLELPSRSATKDEILRLHTEEHFERLKETSGIRDDERMEE 187
            ::|.|..:|...:|...|...:...........|...|:|..||.|:.|:|.|..  :..||.|.
plant    37 EKHPENADRVRNMLSILRRGPIAPHVNWFTGLPAIVSELLMFHTSEYIEKLVEAD--KSGERCEI 99

  Fly   188 LSSRYDSIYIHPSTFELSLLASGSTIELVDHLVAGKAQNGMAIIRPPGHHAMKAEYNGYCFFNNV 252
            .:..:.|    |.::|.:|||:|:|:..:.|::....:...|::||||||:...:.:||||.||.
plant   100 AAGTFMS----PGSWEAALLAAGTTLSAMQHILDCHGKIAYALVRPPGHHSQPTQADGYCFLNNA 160

  Fly   253 ALATQHALDVHKLQRILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFW--PHLHESDYHA 315
            |||.:.||:.....|:.:||.|||:|.||...||...:|:..|:| ..||| |  .|..:.....
plant   161 ALAVKLALNSGSCSRVAVIDIDVHYGNGTAEGFYTSDKVLTVSLH-MNHGS-WGSSHPQKGSIDE 223

  Fly   316 IGSGAGTGYNFNVPL-NATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALGCPEGEMEV 379
            :|...|.|||.|||| |.||....:|  ...:|::|....|.|:::::..|.|::...|.|...:
plant   224 LGEDVGLGYNLNVPLPNGTGDRGYEY--AMNELVVPAVRRFGPDMVVLVVGQDSSAFDPNGRQSL 286

  Fly   380 TPACYPHLLNPLLRLAD----ARVAVVLEGG-------YCLDSLAEGAALTLRSLLGDPCPPLVE 433
            |...|..:...:..:|:    .|:.:|.|||       |||.::.||........|.||    :.
plant   287 TMNGYRRIGQIMRGVAEEHSHGRLLMVQEGGYHVTYAAYCLHAMLEGVLKIPEPHLSDP----IA 347

  Fly   434 TVPLPRAELAQALLSCIAVH 453
            ..|...|....|:.|....|
plant   348 YYPEEEANAVAAVESIKTYH 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC6	NP_001259569.1	HDAC10_HDAC6-dom1	119..457	CDD:212526	105/345 (30%)
		HDAC6-dom2	538..895	CDD:212527
		zf-UBP	1007..1069	CDD:460464
HDA08	NP_563817.1	HDAC_classII_1	6..351	CDD:212521	100/327 (31%)