Protein Alignment HDAC6 and HDA14

DIOPT Version :10

• Sequence 1: NP_001259569.1
• Gene: HDAC6 / 32461
• FlyBaseID: FBgn0026428
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: NP_567921.1
• Gene: HDA14 / 829484
• AraportID: AT4G33470
• Length: 423
• Species: Arabidopsis thaliana
• Alignment Length: 346
• Identity: 116/346 - (33%)
• Similarity: 175/346 - (50%)
• Gaps: 49/346 - (14%)

  Fly   539 DAQMLLHCNL----NDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSP-------------RAATT 586
            ||:::...:.    |...|||..:|:..|..       ..:|.:|:|             :.||.
plant    62 DARLIYSVSAALGHNKESHPECSARVPAIVN-------ALEMNELTPKFRGSQILELANFKTATV 119

  Fly   587 DEVCLAHTRAHVNTVRRLLGREPKELHDAAGIY----NSVYLHPRTFDCATLAAGLVLQAVDSVL 647
            :::...|.:|:|..:.:.:    .|..|:..|:    ...|....||..:.:|||..:..||||:
plant   120 EDIANVHDKAYVFGLEKAM----DEASDSGLIFIEGSGPTYATSTTFQDSLIAAGAGMALVDSVI 180

  Fly   648 RGESRS-----GICNVRPPGHHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNG 707
            .....|     |...:|||||||....|.|||:|.||||||::|.|..||:|:.|:|:|||||||
plant   181 AASRNSVDPPIGFALIRPPGHHAVPKGPMGFCVFGNVAIAARHAQRTHGLKRIFIIDFDVHHGNG 245

  Fly   708 TQHIFESNPKVLYISLHRYEHGSFFPKGP-DGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAF 771
            |...|..:|.:.::|.|  :.||:    | .|....:|||.|.|..:|:|. ..|.||:.....|
plant   246 TNDAFTEDPDIFFLSTH--QDGSY----PGTGKISDIGKGKGEGTTLNLPL-PGGSGDIAMRTVF 303

  Fly   772 QQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGMLTHWLSALA----SGRIIVCLEG 832
            :::|:|.|..|.|.::|||||:||.:.|||...:.|...|..|...:..||    .||.:..|||
plant   304 EEIIVPCAQRFKPDIILVSAGYDAHVLDPLANLQFTTATYYSLAKDIKRLAKEVCGGRCVFFLEG 368

  Fly   833 GYNVNSISYAMTMCTKTLLGD 853
            |||:.|:|.::....:.|||:
plant   369 GYNLESLSSSVADSFRALLGE 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC6	NP_001259569.1	HDAC10_HDAC6-dom1	119..457	CDD:212526
		HDAC6-dom2	538..895	CDD:212527	116/346 (34%)
		zf-UBP	1007..1069	CDD:460464
HDA14	NP_567921.1	HDAC_classII	80..387	CDD:212518	110/324 (34%)