Protein Alignment HDAC6 and Hdac8

DIOPT Version :9

• Sequence 1: NP_001259569.1
• Gene: HDAC6 / 32461
• FlyBaseID: FBgn0026428
• Length: 1179
• Species: Drosophila melanogaster
• Sequence 2: XP_006528338.1
• Gene: Hdac8 / 70315
• MGIID: 1917565
• Length: 386
• Species: Mus musculus
• Alignment Length: 325
• Identity: 97/325 - (29%)
• Similarity: 158/325 - (48%)
• Gaps: 26/325 - (8%)

  Fly   536 YAYDAQMLLHCNLNDTGHPEQPSRIQHIHKMHDDYGLLKQMKQLSPRAATTDEVCLAHTRAHVNT 600
            |.|..:.:..|:    ...:.|.|...:|.:.:.|.|.|||:.:.|:.|:.:|:...||.|::..
Mouse    18 YIYSPEYVSICD----SLVKVPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQH 78

  Fly   601 VRRLLGREPKELHDAAGIYNSVYLHPRT---FDCATLAAGLVLQAVDSVLRGESRSGICNVRPPG 662
            ::: :.:|..|.|..:..|...|..|.|   ||.|....|..:.|...::.|:.:..| |.....
Mouse    79 LQK-VSQEGDEDHPDSIEYGLGYDCPATEGIFDYAAAIGGGTITAAQCLIDGKCKVAI-NWSGGW 141

  Fly   663 HHAEQDHPHGFCIFNNVAIAAQYAIRDFGLERVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYE 727
            |||::|...|||..|:..:......|.|  :|:|.||.|:|||:|.:..|....||:.:|||::.
Mouse   142 HHAKKDEASGFCYLNDAVLGILRLRRKF--DRILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFS 204

  Fly   728 HGSFFPKGPDGNFDVVGKGAGRGFNVNIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAG 792
            .| |||  ..|:...||.|.||.::||:| .:.|:.|.:|....:.::..:...|||:.|::..|
Mouse   205 PG-FFP--GTGDMSDVGLGKGRYYSVNVP-IQDGIQDEKYYHICESVLKEVYQAFNPKAVVLQLG 265

  Fly   793 FDAAIGDPLGGCKVTAEGYG----MLTHW-LSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLG 852
            .|...|||:....:|..|.|    .:..| |:.|..|      .||||:.:.:...|..|..:||
Mouse   266 ADTIAGDPMCSFNMTPVGIGKCLKYVLQWQLATLILG------GGGYNLANTARCWTYLTGVILG 324

  Fly   853  852
            Mouse   325  324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC6	NP_001259569.1	HDAC10_HDAC6-dom1	119..457	CDD:212526
		HDAC6-dom2	538..895	CDD:212527	96/323 (30%)
		zf-UBP	1007..1069	CDD:280334
Hdac8	XP_006528338.1	HDAC8	16..370	CDD:212524	97/325 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810