DRSC/TRiP Functional Genomics Resources

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Protein Alignment HDAC6 and Usp51

DIOPT Version :9

Sequence 1:NP_001259569.1 Gene:HDAC6 / 32461 FlyBaseID:FBgn0026428 Length:1179 Species:Drosophila melanogaster
Sequence 2:NP_001131019.1 Gene:Usp51 / 635253 MGIID:3588217 Length:661 Species:Mus musculus


Alignment Length:143 Identity:36/143 - (25%)
Similarity:57/143 - (39%) Gaps:31/143 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   948 RPSGSKPKVKVKTLSDYLAENKEALEQSEMFAVYPLK---TCPH-------------LRLL---- 992
            || |.:|:.:....||:.:.......::.:..|...|   .|.|             ||::    
Mouse   111 RP-GPRPQTRKSYSSDHGSSRDSDGSENSLLEVGSNKGPTGCCHVESFKVAKNWQRNLRMIYQRF 174

  Fly   993 ----RPEEAPRSLDSGAECSVCGSTGENWV--CLSCRHVACGRYVNAHMEQHSVEEQHPLAMSTA 1051
                .||...|...| ..|.:| ||.:|.:  ||||....|  :.:.|:..|:...||.||:...
Mouse   175 IWSGTPETRKRKAKS-CICQIC-STHKNRLHSCLSCVFFGC--FTDKHIHIHAETTQHNLAVDLC 235

  Fly  1052 DLSVWCYACSAYV 1064
            ...::|:.|..||
Mouse   236 HGVIYCFMCRDYV 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HDAC6NP_001259569.1 HDAC10_HDAC6-dom1 119..457 CDD:212526
HDAC6-dom2 538..895 CDD:212527
zf-UBP 1007..1069 CDD:280334 20/60 (33%)
Usp51NP_001131019.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..144 7/33 (21%)
zf-UBP 192..252 CDD:307999 20/60 (33%)
Peptidase_C19D 320..654 CDD:239125
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1867
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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